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rheumatology > rheumatoid arthritis > Flashcards

rheumatoid arthritis Flashcards

1
Q

how do you diagnose the myositis?

A

proximal muscle biopsy, anti Jo-1

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2
Q

what complication are you concerned about for the myositis?

A

malignancy

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3
Q

what is the schober test for?

A

ankylosing spondylitis

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4
Q

scleroderma patients w/ dyspnea on exertion diagnosed w/ diffuse are most likely to have what?

A

pulmonary fibrosis

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5
Q

treatment for raynaud’s?

A

cold avoidance and CCB

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6
Q

a 6 y/o that’s ANA positive and 4 painful joints presents to the clinic, what is the treatment?

A

send to optho for iritis

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7
Q

what is the MC inflammatory arthritis?

A

rheumatoid arthritis

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8
Q

what category of systemic sclerosis is associated w/ pulmonary hypertension?

A

limited

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9
Q

common drugs that affect gout?

A

HCTZ, niacin, ASA, alcohol

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10
Q

what lab is assocaiated w/ psoriatic arthritis?

A

uric acid

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11
Q

first line treatment for ankylosing spondylitis?

A

NSAIDS, refer cardiology and ophthamology

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12
Q

what is MC presenting feature of polymyositis and dermatomyositis?

A

muscle weakness, but no pain

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13
Q

what are the genetic risk factors in sjogren’s?

A

anti-ro and LA, hypergammaglobinemia IgG

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14
Q

what do you give as treatment to avoid blindness in giant cell arteritis?

A

low dose aspirin

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15
Q

what does CREST stand for?

A 
Calcinosis cutis
Raynauds syndrome
Esophageal dysmotility
Sclerodactyly
Telangectasis
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16
Q

what genetic risk factor is associated w/ limited sclerosis?

A

anti-centromere

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17
Q

mother positive for SSA/ SSB what are you concerned the baby will have?

A

heart block in

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18
Q

31 y/o shows up with new onset raynauds what do you do?

A

ANA and naifold capillary exam

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19
Q

what disorder is improved by exercise but not improved by rest?

A

ankylosing spondylitis

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20
Q

what is the most important complication of sjogren’s?

A

lymphoma

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21
Q

what is the MC form of chilhood arthritis?

A

juvenile idiopathic arthritis (oligoarticular?)

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22
Q

who is behcet’s syndrome common in

A

young adults 25-35, turkish, middle eastern, asian

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23
Q

renal crisis is commonly associated w/ what disease and what is the treatment?

A

systemic sclerosis, ACEI

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24
Q

fibromyalgia is primarily manifested by what?

A

diffuse pain and fatigue

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25
Q

what groups do the myositis affect?

A

proximal muscle groups symmetrically

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26
Q

you have a woman that’s 30 y/o that comes into the ER w/ rheumatoid arthritis and complains of chest pain what should you do?

A

work up for MI because the rheumatoid predisposes you to younger cardiovascular disease

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27
Q

which of the lupus are most sensitive to photosensitive?

A

subacute cutaneous

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28
Q

a pateitn presents w/ a rash on their face and hands, but the hands spare the extensor surfaces, what does this person have?

A

actue cutaneous lupus

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29
Q

what is the most common heart defect associated w/ ankylosing spondylitis?

A

1st degree AV block

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30
Q

someone 25-35 of turkish or middle eastern descent w/ a vasculitis issue would most likely have this genetic risk factor?

A

HLA-B51

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31
Q

what is the MC presenting feature of SLE?

A

arthritis

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32
Q

what is the schirmer test associated w/?

A

sjogren disease

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33
Q

what is the treatment for the myositis?

A

high dose corticosteroid

34
Q

what will be positive in a patient with drug induced lupus?

A

anti-Histone

35
Q

what category of systemic sclerosis is associated w/ intersitital lung disease and pulmonary fibrosis?

A

diffuse

36
Q

what is the treatment for takyasu?

A

high dose prednisone

37
Q

what are the signs that are associated w/ the dermatomyositis?

A

heliotrope rash, shawl sign, gottron’s sign, mechanics hands

38
Q

scleroderma patients w/ dyspenea on exertion diagnosied w/ limited are most likely to have what?

A

pulmonary HTN

39
Q

a woman presents presents w/ symmetric joint pain that spares the DIP, fever, anemia, dry mouth and dry eyes, what does she have and what is the best treatment?

A

rheumatoid arthritis with extraarticular sjogren syndrome, methotrexate, w/ NSAID/corticosteroid bridge. also make sure that the person stays active

40
Q

people with sjogrens are at an increased risk for what?

A

lymphoma

41
Q

what is the prognosis for systemic sclerosis?

A

18-24 months, then it starts to get better

42
Q

what are the genetic risk factors for lupus?

A

ANA, anti-Sm, anti-dsDNA, SSA, SSB, anti-histone, decreased compliment during flare

43
Q

what does psoriatic arthritis mimic?

A

RA, but RF negative

44
Q

<7 y/o female complains of pain in <=4 joints that the parents though initially thought was growing pains, but it isnt in the joint. What lab would you test, what complication are you worried about, and what is the diagnosis?

A

ANA, iritis, oligoarticular JIA

45
Q

when do you start treatment with DMARDS for patient with rheumatoid arthritis?

A

immediately

46
Q

anti-ro is what?

A

SSA

47
Q

if anticentromere is negative which scleroderma is it unlikely to be?

A

diffuse

48
Q

what group of people are associated w/ systemic scleosis?

A

choctaw indians

49
Q

what will show for lupus nephritis?

A

proteinuria/hematuria

50
Q

what is the age group for oligoarticular arthritis?

A

1-7 y/o and <4 joint groups

51
Q

what do you need to test for before give a biologic DMARD?

A

TB, hep B, C, lymphoma

52
Q

what is the treatment for all the spondyloarthropathies except for enteropathic?

A

nsaid

53
Q

who do we not give corticosteroid to?

A

scleroderma because of renal crisis

54
Q

what drugs will cause a drug induced lupus?

A

chlorpromazine, methyldopa, hydralzine, procainamide, isoniazid, quinidine

55
Q

what do patients w/ scleroderma need to have as part of their diagnosis?

A

raynauds

56
Q

scaly erythematous annular rash that spares the face, located on torso and limbs. they were in the sun and then the rash came, what lab would you expect them to be positive for?

A

anti-Ro SSA

57
Q

what is the MC type of vasculitis in adults?

A

giant cell arteritis`

58
Q

when I get cold my hands will become red, then white, then blue, within 1 year I developed rapid changes in skin texture, w/ sever arthralgia, weight loss, and tendon friction rubs. I also have dyspenea and hypertension?

A

diffuse scleroderma

59
Q

what is the hallmark of bechet?

A

panful apthous ulcers

60
Q

if somebody has polymylagia rheumatica what should you be considering and why?

A

giant cell arteritis because of the risk of vision loss

61
Q

what has the strongest association w/ raynauds phenomenon?

A

systemic sclerosis

62
Q

how long do you need to have back pain for ankylosing spondylitis?

A

> 3 monts

63
Q

what does hla dr3 cause?

A

lupus and sjogren

64
Q

what is the genetic risk factor for behcet’s?

A

HLA-B51

65
Q

what is the age group for seronegative polyarticular JIA?

A

8-12 y/o

66
Q

what is the MC patten or psoriatic arthritis?

A

asymmetric oligoarthritis or hands and feet

67
Q

what genetic risk factor is associated diffuse sclerosis?

A

Scl 70

68
Q

what is associated w/ arteries and veins and all 3 sizes of vessels?

A

behcet

69
Q

what is a common sign of psoriatic arthritis?

A

nail pitting, pencil in cup

70
Q

what is the leading cause of death w/ lupus?

A

end stage renal disease?

71
Q

how long is someone’s eyes dry for in sjogren?

A

> 3 months, also it’s kerato sicca is MC sign

72
Q

what is the antibody specific to mixed connective tissue disease?

A

anti-u1-RNP (high ana w/ speckeled pattern)

73
Q

what are the other names for takayasu’s arteritis?

A

pulseless, or occlussive thromboarotopathy

74
Q

a teenage girl presents w/ >=5 joint groups pain, RF+, what is most likely her condition?

A

seropositive polyarticular

75
Q

what is the MC cause of death in mixed connective tissue disease?

A

pulmonary HTN

76
Q

what markers are the most accurate to monitor lupus and what are the most useful?

A

complement and anti-dsDNA most accurate, ESR and CRP most useful

77
Q

anti-la is what?

A

SSB

78
Q

if someone has a positive anti-Jo-1, what complication are you concerned about?

A

malignancy

79
Q

30-40y/o woman presents w/ chest pain in the ER. the nurse said she had a rheum disorder, but can’t remember what she said. What genetic risk factors would most support the disease that correlates w/ MI?

A

HLA-DRB1, anti-ccp, RF, and it’s rheumatoid arthritis

80
Q

if someone had unilateral parotid gland enlargement with dry eyes and dry mouth what are you concerned for?

A

lymphoma

81
Q

what are some keys to all the seronegative spondyloarthopathies?

A

HLA-B27, uveitis, absence of autoantibodies, RF factor negative

82
Q

treatment for osteoporosis prevention

A

Stop smoking, Weight-bearing exercise, Calcium/Vitamin D, & Bisphosphonate

rheumatology (2 decks)

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