Rheumatoid Arthritis Flashcards
What ae the main risk factors for Rheumatoid Arthritis?
Female
HLA DR4
Smoking
What joints are spared in Rheumatoid Arthritis?
DIP
What hand deformaties are found in Rheumatoid Arthritis?
ulnar deviation
Z-shaped thumb
Boutonnier’s
Swan Neck
What is boutonnier’s Deformity?
Fixed flexion of the PIP joint
Name some extra-articular signs in Rheumatoid Arthritis (10)
Sjogren's Snydrome lymphadenopathy Pleural Effusion Pericarditis Splenomegaly Amyloidosis of kidneys Carpel tunnel Palmer erythema Leg ulcers Ankle odema
What should be included in DDx in Rheumatoid Arthritis? (3)
OA
psoriatic arth
gout
How is Rheumatoid Arthritis diagnosed (clinically and biochemicaly)?
Joint involvement RF ESR/CRP Symptoms >6 wk ornign stuffness >1h
What drug groups can be used in the Rx of Rheumatoid Arthritis?
DMARDs
NSAIDs
corticosteroids
biologic agents
What DMARDs are used in Rheumatoid Arthritis?
Methotrexate
Hydrocychloroquine
Sulphasalazine
What Biologics are used in Rheumatoid Arthritis?
Inflixumab
Rituxumab
What other aspect of a patients health should be controlled using drugs in Rheumatoid Arthritis?
Cardiac disease
What is Sjogren’s syndrome?
Dry eyes and dry mouth in RA
What is Felty’s Syndrome?
RA, splenomegaly and leucopenia
What dermatological condition can occur in patients with extraarticular signs in Rheumatoid Arthritis?
pyoderma gangernomsum
