Rheumatoid Arthritis Flashcards
What is the definition Rheumatoid Arthritis
Type 3 hypersensitivity that affects joints but can also affect other organs
What are the 4 types of hypersensitivities
Type1: IgE (hypersens)
Type2: IgG + IgM (Ab Mediated)
Type3: Immune Complex mediated
Type4: CD4/8 Mediated
Which HLA are associated with Rheumatoid Arthritis
HLA1/4
What are the 3 signs found in the hands of Rheumatoid Arthritis Px
Boutonniere Deformity
Swan Neck Deformity
Ulnar Deviation
What sign / syndrome is fund in the wrist of Rheumatoid Arthritis Px
Carpal Tunnel Syndrome
What sign is found in the feet of Rheumatoid Arthritis Px
Subluxation of Toes
What 2 conditions are increased in Cardiovascular + respiratory system with Rheumatoid Arthritis
Atherosclerosis
Pulmonary Fibrosis
when investigating Rheumatoid Arthritis, what factor is present in how many Px
80% px = RH factor
What 2 things are raised in Rheumatoid Arthritis
ESR + CRP
What antibodies are found in Rheumatoid Arthritis
CCP Antibodies
What conservative treatment is used in Rheumatoid Arthritis
Exercise
What 2 disease modifying antirheumatic drugs (DMARDS) used in Rheumatoid Arthritis
Methotrexate
Sulfasalazine
What are 2 complications that can arise from Rheumatoid Arthritis (heart + glands)
Pericarditis
Sjogren’s Syndrome