Rheumatoid antibodies

Question 1

What antibodies are commonly seen in rheumatoid arthritis?

Answer 1

Rheumatoid factor (RF)

Question 2

What antibodies are commonly seen in SLE?

Answer 2

Anti-dsDNA

Question 3

What antibodies are specific to SLE?

Answer 3

Anti-Smith

Question 4

What antibodies are specific to rheumatoid arthritis?

Answer 4

Anti-CCP

Question 5

What antibodies are seen in Sjogren’s?

Answer 5

Anti-Ro and Anti-La

Question 6

Which antibodies must be positive for a diagnosis of SLE?

Answer 6

ANA antibodies

Question 7

What two things are commonly positive / raised in Sjogren’s?

Answer 7

ANA and IgG

Question 8

What investigations should be done in APS?

Answer 8

Lupus anticoagulant
Anticardiolipin
Anti-beta 2 glycoprotein

Question 9

What antibodies are seen in myositis?

Answer 9

Anti-Jo-1
AntiSRP

Question 10

What antibodies are seen in diffuse systemic sclerosis?

Answer 10

Anti-Scl70
Anti-RNA polymerase III

Question 11

What antigen is seen in all spondyloarthropathies?

Answer 11

HLA-B27

Question 12

What is positive in eGPA?

Answer 12

p-ANCA and anti-MPO

Question 13

What is positive in GPA?

Answer 13

c-ANCA and anti-PR3

Question 14

What is positive in MPA?

Answer 14

p-ANCA and anti-MPO

Question 15

What is negative in Henoch-Schonlein Purpura?

Answer 15

ANCA

Question 16

What antibodies are specific to dermatomyositis?

Answer 16

Anti-Mi-2 antibodies