Rheumatic Fever Flashcards
An acute inflammatory disease of the heart potentially involving all layers (endocardium, myocardium, and pericardium)
Rheumatic Fever
A chronic condition resulting from RF that is characterized by scarring and deformity of the heart valves
Rheumatic Heart Disease
Risk factor of Rheumatic Fever
-Untreated Group A Beta-hemolytic streptococcal pharyngitis
-Poverty
-Malnutrition
-Maternal unemployment and low level of maternal education
serves as basis for diagnosis
Modified Jones Criteria
Carditis
Most important manifestation
-Heart murmur
-Cardiac or enlargement and HF
-Pericarditis
Monoathritis or Polyarthritis
Most common manifestation
-affects the synovial membranes of the joints, causing swelling, heat, redness, tenderness, and limitation of motion
-frequently affects large joints (i.e., knees, ankles, elbows and wrist)
Major CNS manifestation; late sign and characterized by involuntary movements, especially of the face and limbs; muscle weakness; and disturbances and gait
Sydenham’s chorea (St.Vitus Dance)
Bright pink, nonpruitic, map-like macular lesions occur mainly on the trunk and proximal extremities, and may be exacerbated by heat
Erythema marginatum
Firm, small, hard, painless swellings located over extensor surfaces of joints, particularly the knees, wrists, and elbows
Subcutaneous nodules
Used as supplemental data to confirm the presence of RF when only one major criterion is present
Minor Criteria
Evidence of Infection are confirmed by:
-Elevated ASO titer
-positive throat culture
-positive rapid test for GABHS
A blood test to measure antibodies against streptolysin O, a substance produced by group A streptococcus bacteria
Antistreptolysin O (ASO) Titer
Positive result of ASO titer
> 200 IU/ml
Medical Management of Rheumatic Fever
-Antibiotic Therapy
-Salicylates (Aspirin) or NSAIDS
-Corticosteroids
-Antibiotic Prophylaxis
Used when arthritis is the main manifestation
Salicylates or NSAIDs