Rheuma

Question 1

Polyarteritis Nodosa - more prevalent in?

Answer 1

Males and females

Question 2

Associations with PN

Answer 2

Hep B, C, hair cell leukemia

Question 3

PN commonly affects

Answer 3

Kidney, skin, joint, muscle, peripheral nerve, GI (spares lung)

Question 4

PN sx

Answer 4

Skin-tender, erythematous nodules, purpura, livedo reticularis, ulcers, bullous or vesicular eruptions, commonly on lower extremity, biopsy helpful

Question 5

PN can cause GI inflammation?

Answer 5

True

Question 6

PN can cause foot drop?

Answer 6

True - inflammation compromises the nerve

Question 7

What is livedo reticularis

Answer 7

Blanching or lacy appearance to the skin. Red and white areas.

Question 8

What cause livedo

Answer 8

Vasculitis (like PN), some people have physiologic (our norm), antiphospholipid syndrome, smoking, heating pad burns

Question 9

Is livedo diagnostic of vasculitis

Answer 9

No

Question 10

What are common causes of elevated liver associated enzymes? What cause shouldn’t you forget?

Answer 10

Never forget that another cause is muscle - if inflammation in muscle (elevated CPK), you may also see elevated ALT, AST

Question 11

What are Polymyositis/Dermatomyositis

Answer 11

inflammation of muscle and inflammation of muscle with assoc with the skin characterized by proximal weakness. With PMR you get proximal pain but not really weakness.

Question 12

Can there be joint effects with polymyo or dermatomyo?

Answer 12

Yes

Question 13

What should you look out for with poly and dermato myositis?

Answer 13

Coexisting malignancy

Question 14

Signs and symptoms?

Answer 14

Dilation of blood vessels in nail beds and redness of upper eyelid

Heliotrope rash
Periungual abnormalities

Question 15

What is assoicated with dermato

Answer 15

With lupus it isn’t over the joint with Gottron’s you have inflammation over the joint