Rheum - The GALS Screen Flashcards

1
Q

What does GALS stand for?

A

G - gait
A - arms
L - legs
S - spine

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2
Q

What do you do as part of the GALS examination?

A

Observe the patient walk, turn & walk back

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3
Q

What key questions do you ask as part of the GALS examination?

A

o Have you any pain in your muscles, joints or back?

o Can you dress yourself completely without any difficulty?

o Can you walk up and down the stairs without any difficulty?

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4
Q

What do you examine as part of the gait?

A

Observe the patient walk, turn & walk back
• smoothness & symmetry of leg
• normal stride length
• ability to turn quickly

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5
Q

When examining inflammation, what should you be looking out for?

A
  • Rubour (red)
  • Calor (hot)
  • Tumour (swelling)
  • Dolor (pain)
  • Funcio laesa (loss of function)
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6
Q
Define the locomotor examination terms:
Arthritis
Arthralgia
Dislocation
Subluxation
Varus deformity
Valgus deformity
A

 Arthritis
– refers to a definite inflammation of a joint(s)

 Arthralgia
– refers to a pain within a joint(s) WITHOUT demonstrable inflammation by physical examination

 Dislocation
– articulating surfaces are displaced and no longer in contact

 Subluxation
– partial dislocation

 Varus deformity
– lower limb deformity whereby distal part is directed towards the midline – e.g. varus knee with medial compartment osteoarthritis

 Valgus deformity
- lower limb deformity whereby distal part is directed distally from the midline – e.g. hallux valgus.

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7
Q

What is a good example of arthritis and explain it

A

Acute gout
• disease where deposition of MSU crystals in the tissue
• due to hyperuricemia

MSU - monosodium urate

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8
Q

What can acute gout lead to?

A

Could lead to one or more of the following:

  1. Gouty arthritis
    • commonly affects the 1st MTP joint (podagara)
    • abrupt onset, painful, all cardinal inflammation signs, resolved over 3-10days
  2. Tophi
    • aggregated deposits of MSU in tissue
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9
Q

For joint swelling, identify:

(1) site of swelling
(2) tissue involved
(3) Indicative of

A
  1. Articular soft tissue
    • joint synovium OR effusion
    • inflammatory joint disease
  2. Periarticular soft tissue
    • subcutaneous tissue
    • inflammatory joint disease
  3. Non-articular synovial
    • bursa/tendon sheath
    • inflammation of structure
  4. Bony areas
    • articular ends of bones
    • osteoarthritis
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10
Q

Explain what is meant by enthesopathy

A

Pathology at the enthesis
• where the ligament/tendon inserts into the bone

Example
• achilles tendonitis, plantar fasciitis

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11
Q

Signs of irreversible joint damage?

A

Joint deformity
• malalignment of 2 articulating bones

Crepitus
• sound upon articulating joint (i.e. in osteoarthritis)

Loss of joint range OR abnormal movement

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12
Q

What chronic condition is a good example of where joint deformity may occur?

A

Ankylosing Spondylitis

Leads to/affects 
 • sacroiliac joints & spine 
 • Entheses --> chronic enthesopathy
 • Non-axial joints (i.e. hips & shoulders)
 • RF is -VE
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13
Q

Signs of mechanical defect?

A

May be due to inflammation, degenerative arthritis OR trauma

Identify by:
• painful restriction of motion in absence of features of inflammation (e.g. knee locking)
• Instability (e.g. side-to-side movement of tibia on femus)

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14
Q

So, what do you ALWAYS ask in terms of the NATURE of the joint abnormality?

A
  1. Is there INFLAMMATION?
  2. Is there IRREVERSIBLE JOINT DAMAGE?
  3. Is there a MECHANICAL DEFECT
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15
Q

What do you ask after finding out the nature of the joint abnormality?

A

What is the EXTENT (distribution) of the joint involvement?

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16
Q

Explain how you would measure the EXTENT of joint involvement

A

Determine the number of joints involved:
• Polyarthritis >4
• Oligoarthritis 2-4
• Monoarthritis 1

 Note symmetrical involvement
 Note size of involved joints
 Note any axial involvement

17
Q

Examples of conditions and the extent of joint involvement?

A
  1. RA
    • bilateral, symmetrical
    • large & small joints
  2. ReA
    • lower limb, asymmetrical
    • oligoarthritis
    • axial involvement
  3. Gout
    • exclusive 1st MTP joint involvement

(onenote!!)

18
Q

Final question you ask and describe it

A

Are any OTHER FEATURES of diagnostic importance present?

RA = subcutaenous nodules
Gout = tophi
SLE = malar rash
19
Q

What is synovial fluid and how is it synthesised?

A

Viscous fluid present in the space of synovial joints

Synthesised by synovial living cells, type A and type B
• Type A - macrophage-like cells
• Type B - fibroblast-like cells

Type B secrete hyaluronic acid = increased viscosity of synovial fluid

20
Q

What is meant by synovial effusion?

A

Abnormal increase in synovial fluid volume

21
Q

2 ways synovial effusion can form?

A
  1. Normal composition
    • abnormal mechanical stimulation (i.e. osteoarthritis) = increases hyaluronic acid production
    • more oncotic pressure = increased synovial fluid volume
  2. Abnormal composition
    • synovitis due to inflammation = inflammatory exudate
22
Q

Types of synovial effusions?

A
  1. Normal
  2. Non-inflammatory
    • osteoarthritis
    • 10-20% neutrophils
  3. Inflammatory
    • gout
    • 20-70% neutrophils
  4. Infectious
    • bacterial infections
    • 70%+ neutrophils
23
Q

When is synovial fluid examination mandatory?

A

When joint infection is suspected

Confirms diagnosis of suspected crystal arthritis as well

24
Q

Explain how synovial fluid examination is conducted, contraindications and complications

A

Performed using needle aspiration – “arthrocentesis”
Contraindications include:
• bleeding disorders (genetics or drugs like warfarin), overlying skin infection

Complications include:
• introducing infection, Haemarthrosis, damage to structures

25
Q

Synovial fluid samples are routinely examined for pathogens and crystals - explain how

A

Synovial fluid is gram stained –> cultured –> antibiotic sensitivity assay

 Polarising light microscopy detects crystals which can be seen in gout and pseudo-gout.

26
Q

Key points regarding connective tissue disorders?

A

o Arthralgia (pain within a joint with NO inflammation) AND arthritis are typically NON-EROSIVE

o Serum antibodies are characteristic
– aid diagnosis, correlate with disease activity, may be pathogenic

Raynaud’s phenomenon is common in these conditions:
 Intermittent vasospasm of digits on exposure to the cold
 Colour changes (blue  red) – vasospasm blanches digit, cyanosis as static venous blood deoxygenates, reactive hyperaemia.

27
Q

What is included in connective tissue disorder?

A
  • SLE
  • Inflammatory muscle diseases
  • Systemic sclerosis
  • Sjogren;s syndrome
  • Overlap syndrome (mixture of above)
28
Q

Clinical manifestations of SLE?

A

Prototypic AI disease typically diagnosed in female ages 15-45

  • Malar rash
  • Photosensitive rash
  • Mouth ulcers
  • Hair loss
  • Raynaud’s phenomenon
  • Arthralgia (sometimes arthritis)
  • Serositis
  • Renal & CNS disease