Rheum Info From Books

Question 1

What joint in hands is not generally associated with RA, but is seen in OA

Answer 1

DIP

Question 2

Most common joints in hands affected by RA

Answer 2

MCP

PIP

Question 3

Inflammatory arthritis is aggregated by….

Answer 3

Aggregation with rest (morning stiffness)

Relief with use

Question 4

Non inflammatory arthritis is aggravated by…

Answer 4

Aggregate by motion

Relieved by rest

Question 5

Most common joints affected by OA

Answer 5

Knee
Hip
Spine
Hand joints (PIP, DIP)

Question 6

What hand joint is usually unaffected by OA

Answer 6

MCP

Question 7

Symmetrical joint involvement. Can occur at any joint but common in hands and feet (esp MCP and PIP)

Answer 7

RA

Question 8

Prolonged morning stiffness. Long term can lead to joint deformity and nodule formation

Answer 8

RA

Question 9

Occurs in knee, hip, spine, hand (DIP, PIP)

Answer 9

OA

Question 10

Gradual onset, pain w activity. Short period of morning stiffness

Answer 10

OA

Question 11

Arthritis seen in IV drug users, trauma, prosthetic joints, immunocompromised

Answer 11

Infectious arthritis

Question 12

Most common joint affected by infectious arthritis

Answer 12

Knee

Question 13

An antibody that reacts with a fragment of IgG to form immune complexes

Answer 13

Rheumatoid factor

Question 14

Drug of choice with RA

Answer 14

Methotrexate

Because of its potency and relatively fast acting (improvement seen within in 1 month)

Question 15

Bad thing about using DMARDs

Answer 15

Can take up to 3-4 months to work

Can be toxic and require close monitoring (esp those related to bone marrow suppression)

Question 16

Individuals with this condition appear to have a defective elimination of self reactive B cells with a resultant increase in production of antibodies that can cause tissue damage

Answer 16

SLE

Question 17

Most common drugs that cause drug induced lupus

Answer 17

Hydralazine

Procainamide

Question 18

This antimalarial drug may be helpful in treating mucocutaneous manifestations, pleuritis, arthritis and fatigue in SLE

Answer 18

Hydroxychloroquine

Question 19

Renal and CNS treatment in SLE patients

Answer 19

Corticosteroids

Question 20

When would immunosuppressive drugs, like Azathioprine and cyclophosphamide, be used to treat SLE

Answer 20

Cases resistant to corticosteroid tx

Question 21

Calcinosis

Answer 21

Calcium deposits in subcutaneous tissue that erupt thru the skin

Question 22

Sclerodactyly

Answer 22

Localized scleroderma on the fingers

Question 23

Telangiectasia

Answer 23

Dilated skin capillaries

Question 24

Enthesopathy

Answer 24

Inflammation of insertion of tendons and ligaments to bone

Question 25

Typical characteristics of psoriatic arthritis

Answer 25

Pitting of nails
Sausage finger appearance
Pencil in cup deformities of proximal phalanx on X-ray

Question 26

Psoriatic arthritis mild tx

Answer 26

NSAIDs

Question 27

Psoriatic arthritis tx for skin inflammation and arthritis

Answer 27

Methotrexate

Question 28

Asymmetric arthritis of large joint below the waist
Urethritis
Conjunctivitis

Answer 28

Reactive arthritis

Question 29

Gout initial drug of choice

Answer 29

NSAIDs

Question 30

After NSAIDs, next line of drug used in gout

Answer 30

Colchicine

Question 31

Side effect/reason colchicine use is limited

Answer 31

GI side effects

Question 32

Gout prophylaxis tx

Answer 32

Allopurinol

Question 33

Crescent sign seen with

Answer 33

Avascular necrosis

Question 34

Functions loss with Legg Calve Perthe disease

Answer 34

Abduction

Internal rotation