Rheum Antibodies, genetics, and other stuff Flashcards

1
Q

HLA-B27

A

PAIR: Psoriatic arthritis, ankylosing spondylitis, IBD, reiter syndrome

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2
Q

HLA-DR2

A

SLE

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3
Q

HLA-DR3

A

SLE, Sjogrens

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4
Q

HLA-DR4

A

RA, MCTD

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5
Q

C-ANCA

A

Wegener’s granulomatosis

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6
Q

P-ANCA

A

Churg-Strauss, microscopic polyangiitis (polyarteritis nodosa?)

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7
Q

Anti-basement membrane

A

Goodpastures

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8
Q

Anti-CCP

A

RA

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9
Q

Anti-centromere

A

CREST

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10
Q

Anti-desmosome

A

Pemphigus vulgaris

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11
Q

Anti-dsDNA

A

SLE

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12
Q

Anti-endomysial

A

Celiac Sprue

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13
Q

Anti-Fc IgG (RF)

A

SLE, RA, many others

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14
Q

Anti-gliadin

A

Celiacs

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15
Q

Anti-hemidesmosome

A

Bullous pemphigoid

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16
Q

Anti-histone

A

Drug-induced lupus

17
Q

Anti-Jo-1

A

Polymyositis/dermatomyositis

18
Q

Anti-microsomal

A

Hashimotos

19
Q

Antimitochondrial

A

PBC

20
Q

ANti-nAChR

A

Myasthenia gravis

21
Q

ANA

A

SLE, RA, many others

22
Q

Anti-peroxidase

A

Hashimotos

23
Q

Anti-Scl070 (anti-topoisomerase)

A

Diffuse scleroderma

24
Q

Anti-Sm (smith?)

A

SLE

25
Q

Anti-smooth muscle

A

Autoimmune hepatitis

26
Q

Anti-SSA/SSB (anti-Ro/La)

A

Sjogrens

27
Q

Anti-thyroglobulin

A

Hashimotos

28
Q

Anti-TSH (TSI)

A

Graves

29
Q

Anti-U1-RNP

A

MCTD

30
Q

Anti-VGCC

A

Lambert-Eaton myasthenic syndrome