Rheum Flashcards

1
Q

ank spond management

A
Analgesia
Omeprazole if on NSAIDs
Methotrexate for peripheral disease
Biologics: etanercept (TNFa), secukinumab (Il17)
?Jakinib
Surgical: Hip replacement
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2
Q

Osteoarthritis management

A

analgesia
Physio/hand therapy
Aids for daily living
Injected steroids/hyaluronic acid

consider surgery

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3
Q

Acute gout management

A

NSAIDs (naproxen)
Colchicine
Prednisolone
Anakinra injection

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4
Q

Chronic gout management

A

Low purine diet
weight loss and EtOH avoidance
Allopurinol
Consider uricosuric agents (probenecid)

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5
Q

Rheumatoid Arthritis Management

A
Analgesia + omeprazole
Steroids (pred)
DMARDs (MTX, HCQ, SSZ)
Biologics (etanercept, infliximab)
JAK inhibitors (Jakinib)
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6
Q

Psoriatic arthritis management

A

Physio
Smoking, alcohol, weight loss
Analgesia
Steroids + vitamin D analogues (calcitriol)
DMARDs (Methotrexate, sulfasalazine etc.)
Biologics (etanercept, infliximab etc.)

For skin: emollients, phototherapy

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7
Q

Reactive arthritis management

A

Analgesia

Steroids

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8
Q

Raynaud’s management

A

avoid cold
stop smoking
Nifedipine

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9
Q

Sjogren management

A

artificial tears
paracetamol + NSAIDs
hydroxychloroquine

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10
Q

Lupus management

A

Sun protection, exercise, smoking

NSAIDs + PPI

HCQ
Short term pred + IV cyclophosphamide for flares

If bad
Tacrolimus
Rituximab

Monitor C3/4

Consider ACEi if proteinuria

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11
Q

Dermatomyositis/polymyositis management

A

Steroids
Azathioprine
Methotrexate

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12
Q

Giant Cell Arteritis management

A

USS temporal artery +/- biopsy
high dose pred 60mg

Consider Il6 blocker
if vision loss start methylprednisolone 500mg 3 days

Steroid protection: Vit D/Calcium, PPI, bisphosphonate

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13
Q

HSP management

A

Supportive

Should self-resolve

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14
Q

Osteoporosis management

A
physio
HRT if peri/postmenopausal
bisphosphonates
Anti-RANK (denosumab)
PTH analogues (teriparatide)
anti-sclerostin (romosozumab)
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15
Q

signs of reactive arthritis

A
oligoarthritis, uveitis, urethritis
keratoderma blenorrhagicum 
circinate balanitis
enthesitis
mouth ulcers
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16
Q

investigation for Sjogren’s

A

Schirmer’s test

induce tears and see how much liquid travels on Schirmer strip in 5m

17
Q

CREST syndrome

A
Calcinosis
Raynaud's
Esophageal dysmotility
Sclerodactlyl
Telangiectasia 

skin problems in hands, face and feet only

18
Q

Additional systemic sclerosis symptoms

A

renal -> acute HTN crisis
lungs -> fibrosis
cardiac -> arrhythmia
oesophageal -> GORD, aspiration, dysphagia

19
Q

Management of sclerosis

A
Stop smoking
immunosuppression (MTX, azathio, etc)
Raynaud's control
digit ischaemia: sildenafil
oesophageal -> PPI, prokinetics

acute HTN crisis is managed aggressively with ACEi (consider dialysis)

20
Q

septic arthritis investigations

A
synovial fluid sample
bloods (Gram stain may be false negative in 50%)
cultures
X-ray
USS
21
Q

management of septic arthritis

A
aspirate joint to dryness
Hip: USS guided aspiration and debridement
IV antibiotics
analgesia
refer to orthopods and consider surgery