Rheum Flashcards

1
Q

triad to compose Felty syndrome?

A

RA, neutropenia, spelnomegaly

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2
Q

treating felty sydnrome?

A

abx before DMARD

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3
Q

DMARD used in felty syndrome?

A

MTX then rituxan

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4
Q

tx resistant felty syndrome?

A

splenectomy

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5
Q

arthralgias, skin lesions with palpable purpura, ulceration association with hep c?

A

cryoglobulinemia

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6
Q

labs for SLE?

A

anti DS DNA, anticardiolipin ab

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7
Q

false positive RPR

A

think SLE

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8
Q

manifestion of scleroderma renal crisis?

A

severe HTN, progression to death nd ESRD fast if not treated

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9
Q

antihypertensive to use with scleroderma renal crisis?

A

ACE inhibitor

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10
Q

lab for RA

A

anti ccp

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11
Q

GPA is what kind of disease?

A

pulmonary renal syndrome

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12
Q

Molecular findings of GPA?

A

CANCA agaisnt anti PR3, crescenteric sclerosing glomerulonephritis

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13
Q

tx of GPA in critically ill?

A

Rituxan, steroids, PLEX

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14
Q

GPA lung disease type?

A

cavitary lung disease

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15
Q

neuro symptoms of GPA?

A

mononeuritis multiplex

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16
Q

most common pulmonary renal syndrome?

A

microscopic polyangitis

17
Q

microscopic polyangitis serum tests?

A

P- ANCA, anti MPO ab

18
Q

pulmonary lung disease type as compared with GPA?

A

DAH versus cavitary disease

19
Q

tx of DAH with SLE?

A

high dose steroids and second DMARD like cyclophosphamide followed by pharesis

20
Q

adult onset stills disease major criteria?

A
  1. high fever for a week, 2. arthritis for 2 weeks, 3. salmon colred rash on trunk or extremities, 4. leukocytosis
21
Q

acquired perforating disorder skin lesion? tx?

A

hyperkeratotic with a central keratin crust, tx underlying cause and topical steroids

22
Q

anti CCP ab?

A

RA

23
Q

anti U1 RNP ab?

A

MCTD

24
Q

anti DNA topoisomerase ab?

A

systemic sclerosis

25
Q

anticardiolipin ab?

A

APS

26
Q

lupus anticoagulant

A

APS