Rheum Flashcards
triad to compose Felty syndrome?
RA, neutropenia, spelnomegaly
treating felty sydnrome?
abx before DMARD
DMARD used in felty syndrome?
MTX then rituxan
tx resistant felty syndrome?
splenectomy
arthralgias, skin lesions with palpable purpura, ulceration association with hep c?
cryoglobulinemia
labs for SLE?
anti DS DNA, anticardiolipin ab
false positive RPR
think SLE
manifestion of scleroderma renal crisis?
severe HTN, progression to death nd ESRD fast if not treated
antihypertensive to use with scleroderma renal crisis?
ACE inhibitor
lab for RA
anti ccp
GPA is what kind of disease?
pulmonary renal syndrome
Molecular findings of GPA?
CANCA agaisnt anti PR3, crescenteric sclerosing glomerulonephritis
tx of GPA in critically ill?
Rituxan, steroids, PLEX
GPA lung disease type?
cavitary lung disease
neuro symptoms of GPA?
mononeuritis multiplex
most common pulmonary renal syndrome?
microscopic polyangitis
microscopic polyangitis serum tests?
P- ANCA, anti MPO ab
pulmonary lung disease type as compared with GPA?
DAH versus cavitary disease
tx of DAH with SLE?
high dose steroids and second DMARD like cyclophosphamide followed by pharesis
adult onset stills disease major criteria?
- high fever for a week, 2. arthritis for 2 weeks, 3. salmon colred rash on trunk or extremities, 4. leukocytosis
acquired perforating disorder skin lesion? tx?
hyperkeratotic with a central keratin crust, tx underlying cause and topical steroids
anti CCP ab?
RA
anti U1 RNP ab?
MCTD
anti DNA topoisomerase ab?
systemic sclerosis
anticardiolipin ab?
APS
lupus anticoagulant
APS
