REVISION CONCEPTS Flashcards
1
Q
What is the difference between the coding strand versus the RNA strand?
A
- The Ts in the coding strand are replaced by Us in the RNA strand
2
Q
Which direction is the template strand read in and why?
A
- A 3’–> 5’ direction
- Because RNA must be synthesized in a 5’–> 3’ direction
3
Q
Which enzyme synthesizes RNA and does it need a primer?
A
- RNA polymerase
- Does not need a primer
4
Q
What are the 3 stop codons?
A
- TAG (UAG)
- TAA (UAA)
- TGA (UGA)
5
Q
What are the nonpolar, aliphatic R group amino acids?
A
- MAGLIVP
- Methionine
- Alanine
- Glycine
- Leucine
- Isoleucine
- Valine
- Proline
6
Q
What are the nonpolar aromatic R groups?
A
- Phenylalanine
- Tyrosine
- Trptophan
7
Q
What are the Polar, uncharged R groups?
A
- Glutamine
- Asparagine
- Cysteine
- Threonine
- Serine
8
Q
What are the positively charged R groups?
A
- Histidine
- Arginine
- Lysine
9
Q
What are the negatively charged R groups?
A
- Aspartate
- Glutamate
10
Q
When the pH>pka of the functional group, which form dominates?
A
- Deprotonated form dominates
11
Q
What is pKa defined as?
A
- The pH at which a chemical species will accept or donate a proton
- Low pKa means stronger acid and higher Pr of donating proton
12
Q
When the pH
A
- The protonated form (pretty much saying in an acidic environment, there will be lots of H+)