Revision Flashcards
What is the commonest salivary gland malignancy?
Adenocarcinoma (remember that 80% of all salivary tumours are Pleomorphic adenoma)
In a patient with a ? salivary gland cancer, which nerve must you test?
Facial
Ask if any change in hearing or taste?
Look for symmetry
Check facial movement - raise eyebrows, smile, puff out cheeks
Consider doing corneal reflex (affererent = trigeminal, efferent = facial)
What is Frey’s syndrome?
A complication of surgery to remove parotid tumour. Patient sweats while eating due to abnormal connection between autonomic and facial nerve fibres)
Most likely diagnosis in a patient with chest pain, shock and surgical emphysema?
Oesophageal perforation - a surgical emergency
What is the most common type of hiatus hernia?
Sliding accounts for 80%
Part of the gastro-oesophageal junction enters the thorax
Rolling accounts for 5% (with the rest mixed) and describes the proximal part of the stomach, moving into the thorax (higher risk of strangulation)
Upper 2/3 oesophagus = squamous
Lower 1/3 = adenocarcinoma (barrets)
Why are beta blockers used in the prophylaxis of oesophageal varices?
Reduce portal pressure
(this is important as each time oesophageal varices bleed, the mortality is 20%
What is Heller’s operation used for?
Management of achalasia (muscles of stomach and LOS is divided down to the muscosa)
Where is the anatomical cut-off for an upper GI bleed?
The ligament of Treitz (found at the duodojejunal flexures)
Which condition is treated with a Ramstedt pyloromyotomy?
Pyloric stenosis
Non-bilious vomit and olive in RUQ
What is Meckels diverticulum?
Persistence of the vitello-intestinal duct
Problems are mainly ulceration and haemorrhage as many contain gastric mucosa
Most common site of diverticulosis?
Sigmoid colon
(remember diverticulosis is simply the presence of diverticula)
Itis = inflamed
Diseases = causing pain and change in bowel habit
(gastrograffin enema can be good for detecting diverticulosis)
What are the complications of diverticular disease?
Perforation Bowel obstruction Haemorrhage Fistula Abscess
A Hartmann’s procedure is primarily used for emergency surgery of colorectal tumour/ inflammation. Describe it?
Resection of rectosigmoid colon with closure of anorectal stump and formation of an end colostomy
(there is potential for reversal)
Which 2 tumour markers are used for bowel cancer?
CEA
CA 19-9
Duke’s criteria for colorectal cancer
A = confined to bowel wall (90% survival) B = through bowel wall (60% survival) C = regional lymph nodes (30% survival) D = distant mets (5% survival)
Which gene is faulty in FAP?
Autosomal dominant disruption of APC gene
Which is an important tumour suppressor
Management of anal fissure?
- Examine if possible
- increase fibre and stool softeners
- medical e.g. GTN cream, Botox (helps to relax sphincter)
- surgical for failed medical management
What conditions do you have to rule out in a patient with a perianal abscess?
1) Cancer
2) TB/ immunosupression
3) Crohns’
The main complication of an abscess is fistula formation
What condition needs excluded in a child with a rectal prolapse?
CF
What are the 2 different types of rectal prolapse?
1) Full thickness - prolapse of all layers of the rectum through anus
2) Mucosal - prolapse of rectal mucosa through anus
Anal cancer is rare and associated with HPV and receptive intercourse. Histologically what is the most common type?
Adenocarcinoma
Remember valvulae conniventes are found only in SMALL bowel and cross the entire bowel
Haustra are found in LARGE bowel and do NOT cross the entire bowel
Red currant jelly stool in a baby?
Intussusception
Abdo pain, sausage shaped mass
Surgery only if reduction with an air enema fails
How could you differentiate between a mechanical bowel obstruction and an ileus?
History e.g. if just had bowel surgery and no other risk factors —> ileus from touching bowel is most likely
NO bowel sounds - often tinkling in mechanical obstruction
What are the 2 main complications of a hernia?
Obstruction
Strangulation
Briefly describe the anatomy of the inguinal canal
Floor = inguinal ligament Roof = internal oblique/ transversus abdominus
Anterior wall = external/ internal oblique
Poster = transversalis fascia
What are the contents of the inguinal canal?
Spermatic cord/ round ligament
Genital branch of genitofemoral nerve
Ilioinguinal nerve
What is the difference between a direct and indirect inguinal hernia?
Indirect = enters and passes through inguinal canal and can therefore descend into scrotum (LATERAL to inferior epigastic vessels)
Direct = bulge though weakened posterior wall —> cannot descend into scrotum (Medial to the inferior epigastric vessels)
Hernia superior and medial to the pubic tubercle = inguinal hernia
Hernia inferior and lateral to pubic tubercle = femoral hernia
(more common in older women)
These require surgery due to the higher risk of strangulation/ obstruction
Patient has positive Murphy sign. What is this? How is it performed?
Palpate the gall bladder with 2 fingers
Ask the patient to take a deep breath in - this will push the liver + gall bladder causing pain and sharp stop of breathing in a patient with CHOLECYSTITIS
What is the difference between ascending cholangitis and cholecystitis?
Cholangitis = gall stone impacted in CBD —> infection and jaundice (classically jaundice, RUQ and fever)
Cholecystitis = stone impacts and blocks gall bladder outlet
Thrombophlebitis migrants = tender nodules in affect blood vessels. What are they associated with?
Pancreatic and lung cancer
What is Courvoisiers Law?
In jaundice, if the gall bladder is palpable then it is unlikely to be due to stones
Dercums disease?
Typical patient is an obese middle aged female with multiple, tender lipomas
What is Fournier’s Gangrene?
Necrotizing fasciitis of the penis/ scrotum
(more common in alcoholics/ immunosupressed etc)W
What is Marjolin’s ulcer?
An SCC which develops in a chronic ulcer
Breslow thickness <1mm —> 5 year survival is 95-100%
> 4mm —> 5 year survival is <50%
1st line treatment for heart failure = ACEI + Beta blocker
2nd line = spironolactone, ARB or hydralazine + nitrate
Digoxin + cardiac re-synchronisation therapy is 3rd line
Which additional heart sound is most likely in left sided heart failure?
Third heart sound
How is malnutrition diagnosed clinically with regard weight loss?
Unintentional weight loss of >10% within 3-6 months
A Whipples resection is used for pancreatic cancers which are operable. The cancer is removed and the remaining pancreas and duodenum is joined. What is the major complication?
A leak of the anastomoses- monitor drain fluid for amylase. If present then discuss with senior and arrange imaging
This can be potentially fatal
Parkland formula for fluid resuscitation in burn victims
Surface area % x weight in kg x 4ml
What is the cut off for orthostatic hypotension?
Fall in SBP of >20 or DBP of >10
OR systolic BP < 90 on standing
What is hepatorenal syndrome?
A type of progressive kidney failure seen in patients with severe liver damage often cirrhosis
Type 1 = occurs in <2 weeks, doubling of creatinine OR halving of creatinine clearance. Need liver transplant but VERY poor prognosis
Type 2 = slowly progressive, often due to ascites
Nitrates are contraindicated in patients with aortic stenosis due to the risk of profound hypotension
Furesomide is the best option as it will provide symptomatic relief
How should a patient with suspected heart failure be investigated?
Previous MI = echo within 2 weeks
No previous MI = measure BNP, if high then echo within 2 weeks
If raised but not high then echo within 6 weeks
In patients with NAFLD, the enhanced liver fibrosis blood test should be offered to assess advanced fibroisis
It combines hyaluronic acid + procollagen + tissue inhibitor of metalloproteinase 1
Which drug could be used in an old lady who suffers from orthostatic hypotension which has not improved with conservative measures?
Fludrocortisone (it increases Na and H20 reabsorption)
Peugeot Jeghers syndrome
Autosomal dominant
Numerous polyps in the GI tract —> GI bleeding, malignancy and intussusception
Pigmented freckles
Best surgical option for a patient with UC and toxic mega-colon?
Sub-total colectomy
Remove everything apart from the rectum (touching the rectum has a high risk of complications)
(panproctocolectomy with ileoanal pouch is only offered electively)
How do you calculate ABPI?
Highest ankle pressure / highest brachial pressure
<0.9 = PAD
< 0.5 = critical limb ischameia
>1.3 = probably atherosclerosis
(remember that leg pressure should normally be slightly higher)
Why is rest pain worse at night in intermittent claudication?
BP falls at night
Feet are elevated