Review Quiz Flashcards
Systematic reviews synthesise evidence from different types of studies depending on what type of research question is being asked.
A systematic review that syntheses evidence from cohort studies would most likely be answering what type of question?
Prognosis
What is the most fundamental error with this statement about prognosis: ‘People treated with early ACL reconstruction after ACL rupture have a 16% risk of developing osteoarthritis.’
Select one:
a. the physical activity level of the participants is not specified
b. the follow-up time period is not specified Correct
c. it is not clear which grading scale was used to define the presence of osteoarthritis
d. they haven’t identified whether a patellar tendon or hamstring graft was used
B
What are the odds of flipping a coin and landing on tails?
1:1 (1)
Define positive predictive value
If a person tests positive, what is the probability that they have the condition
Define accuracy
What proportion of all tests have given the correct result
Define positive likelihood ratio
How much more likely is a positive test to be found in a person with the condition that a person without the condition
Define specificity
The proportion of people who do not have the condition that the test correctly identifies
Define negative likelihood ratio
How much more likely is a negative test to be found in a person without the condition than a person with a condition
Define sensitivity
The proportion of people who have the condition that the test correctly identifies
Define negative predictive value
If a person tests negative, what is the probability that do not have the condition?
The odds of the event are 1:3, what is the risk (probability) of the event occurring?
1/4 = 25%
As with quantitative studies, large sample sizes are required in qualitative studies to ensure significance and completeness of the research data. True or false?
False
How large must a randomised trial be before the risk of an uneven distribution of confounders between group reaches zero?
This risk never reaches zero
Survival curves are only used in studies of mortality.
True or false?
False
Which of the following factors threaten internal validity of a study?
- Chance
- Bias
- Confounding
- Differences between the study population and the patients that I treat in my clinical practice.
Chance, bias and confounding all threaten internal validity