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HEMA 2 MIDTERMS > REVIEW QUESTIONS > Flashcards

REVIEW QUESTIONS Flashcards

1
Q

Bleeding Time is used to evaluate the activity of:

A

Platelets

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2
Q

Which of the following test results is normal in a patient with classic von Willebrand’s disease?

A

Platelet count

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3
Q

No bleeding is observed in deficiency of which of the following factors?

A

XII

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4
Q

Hemolytic Uremic syndrome is associated with:

A

E.coli

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5
Q

Coagulation Factors affected by Coumarin Drugs:

A

II, VII, IX, X

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6
Q

Thrombotic thrombocytopenic purpura is characterized by:

A

Increase platelet aggregation

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7
Q

A protein that plays a vital role in both coagulation and platelet aggregation:

A

I

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8
Q

The defect characterizing Gray’s Syndrome:

A

Alpha Granule

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9
Q

Factor XIII is activated by which factor?

A

IIa

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10
Q

Factor V is a cofactor to factor X to activate factor II

A

True

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11
Q

What clotting factors are inhibited by Protein S

A

V and VIII

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12
Q

What is the second phase of secondary hemostasis?

A

Activation of Factor X

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13
Q

Several hours after birth, a baby boy develops petechiae and a hemorrhagic diathesis. Platelet count is 8,000/uL. What is likely the explanation?

A

Isoimmune Neonatal Thrombocytopenia

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14
Q

When performing platelet aggregation studies, which is most likely associated with Bernard Soulier Syndrome?

A

Normal to Epinephrine, Decreased to Ristocetin

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15
Q

Which of the following is a characteristics of acute idiopathic thrombocytopenic purpura?

A

Spontaneous remission within a few weeks

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16
Q

Factor XIII is a serine protease

A

False

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17
Q

Which of the following inhibitors inhibit Factor IIa?

A

Both; Protein C and Antithrombin III

18
Q

Which of the following is correct regarding acquired thrombotic thrombocytopenic purpura?

A

Autoimmune Disease

19
Q

TAFI target protein:

A

Fibrin

20
Q

Which step requires calcium?

A

Factor XIII activation

21
Q

Giant platelet is associated with which condition:

A

Bernard Soulier Syndrome

22
Q

Platelet abnormality will affect both bleeding time and clotting time

A

True

23
Q

Which of the following is associated with post transfusion purpura?

A

Immune mediated thrombocytopenia/Alloantibodies

24
Q

Thiazide diuretics results to:

A

Decreased Platelet Production

25
Q

Which of the following Factors is used only in the Extrinsic Coagulation Pathway?

A

VII

26
Q

Hereditary hemorrhagic telangectasia is a disorder of

A

Connective Tissue

27
Q

Which of the following coagulation factors is considered to be labile?

A

V

28
Q

What role does vitamin K play in the Prothrombin group?

A

Carboxylates the factors to allow calcium binding

29
Q

Factor I deficiency will affect APTT and PT

A

True

30
Q

Aspirin prevents platelet aggregation by inhibiting the action of which enzyme?

A

Cyclooxygenase

31
Q

Which statement regarding protein C is correct?

A

Activity is enhanced by Protein S

32
Q

Thrombocytopenia may be associated with

A

Hypersplenism

33
Q

The APTT is sensitive to a deficiency of which clotting factor?

A

None

34
Q

Which of the following factors will activate factor XI?

A

Hageman Factor

35
Q

Lumi-aggregation measures:

A

Aggregation and ATP release

36
Q

APTT is used to?

A

Both; Monitor heparin therapy and evaluate the common pathway

37
Q

Neurologic findings may be commonly associated with which of the following disorders?

A

TTP

38
Q

True of TTP and DIC:

A

APTT prolonged in DIC

39
Q

Which of the following tests is most likely to be abnormal in patients taking Aspirin?

A

Bleeding Time

40
Q

Platelet aggregation response for Glannzmann’s Thrombasthenia

A

Normal to Ristocetin, Decreased to Epinephrine

40
Q

Thrombin-Trombomodulin complex is necessary for the activation of:

A

Protein C

41
Q

Scott syndrome will affect which of the following?

A

Secondary Hemostasis

HEMA 2 MIDTERMS (1 decks)

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