Review Questions

Question 1

The study of how a drug is absorbed, distributed or eliminated from the body is?

Answer 1

Pharmacokinetics

Question 2

Which of the following is FALSE?
1. The therapeutic index is higher in prescription drugs
2. A large TI indicates increase drug safety
3. Therapeutic index (TI) is an indicator of a drugs safety
4. Toxicity is more likely in a drug with a low TI

Answer 2

The therapeutic index is higher in prescription drugs (not true)

Question 3

Which of the following is NOT a form of parental drug administration?
1. Injection
2. rectal
3. topical
4. inhalation

Answer 3

rectal

Question 4

All drugs taken orally are transported to the liver. The liver often metabolizes some of the drug. What is this called?

Answer 4

First Pass Effect

Question 5

Which of the following is a TRUE statement?
1. Agonists are drugs with high affinity but low efficacy
2. Antagonists are drugs that are unable to bind to the cell’s receptor sites
3. Partial agonists have less side effects than agonists
4. mixed agonist-antagonist do not change the cell’s function

Answer 5

Partial agonists have less side effects than agonists

Question 6

Benzodiazepines are commonly prescribed for anxiety. What is a common side effect?

Answer 6

Hangover effect

Question 7

Which of the following is a drug that is considered to be an alternative for sleep hypnosis and does not cause the hang-over effect?

Answer 7

Zolpidem (Ambien)

Question 8

T/F : tolerance and dependence occur with all sedative hypnotic drugs

Answer 8

False

Question 9

Drugs that are commonly used to treat sleep disorders have an increased risk of hip fractures and falls. What should the PT include in each of these patients’ POC?

Answer 9

Environmental modification
Balance Training
LE strengthening
Gait training

Question 10

Antidepressants take how long to become effective?

Answer 10

2-4 weeks

Question 11

What is the primary drug used to treat bipolar disorder?

Answer 11

Lithium

Question 12

Your patient presents with rigidity, bradykinesia, and tremor. These are most likely a side effect of what medication?

Answer 12

Antipsychotic

Question 13

Non-motor side effects of anti-psychotics include all of the following except:
1. weight loss
2. diabetes mellitus
3. increased lipid levels
4. fluctuations in blood sugar

Answer 13

weight loss (should be weight gain)

Question 14

The most feared side effect of anti-psychotics is:

Answer 14

Tardive dyskinesias

Question 15

T/F: Seizures will typically resolve on their own

Answer 15

True

Question 16

T/F: seizure medications will be effective 100% of the time

Answer 16

False

Question 17

Which of the following is TRUE regarding PD medication?
1. Administered 3x/day
2. Levadopa is the drug of choice and administered alone
3. Sinimet is more effective than Levadopa alone
4. Levadopa should be started as soon as one is diagnosed

Answer 17

sinemet is more effective than levadopa alome

Question 18

Great side effect of PD medication is:

Answer 18

dyskinesias

Question 19

Levodopa often becomes less effective once a patient has taken it for 3-4 years.

Answer 19

True

Question 20

Signs of drug tolerance with levodopa include:

Answer 20

Effectiveness of the drug is decreased
End of dose akinesia
On-off phenomenon