Review of IMRT and VMAT Planning Flashcards
Definition of IMRT
Traditional IMRT is delivered using static segments (e.g., step and shoot) or dynamic segments (e.g., DMLC)
Definition of VMAT
A type of rotational IMRT where the MLC and gantry move while the radiation beam is on
IMRT Planning Concepts
- Modulates MLC to shape the 2D beam profile on a fixed angle beam
- Multiple Beams (non-opposing)
- Segments are used
- Beams can be different energies
VMAT Planning Concepts
- Modulates MLC’s, gantry speed and dose rate during beam on to shape 3D dose distribution
- Changing gantry speed and dose rate achieves variable MU per degree during delivery
- No. of arcs depend on complexity of plan
- Partial arcs, non-coplanar arcs can be used
3DCRT Planning Optimisation Strategies
- Altering collimator angles
- Altering wedges (EDW’s)
- Altering beam weights
- Altering margins
- Altering beam attributes if necessary
IMRT Planning Optimisation
- Automated, iterative optimisation techniques
- IMRT prescriptions define the constraints, priorities, and dose objectives for OAR’s and target volumes
What is a target objective?
- A desired treatment goal
What is a constraint and what is it’s purpose?
- A boundary/limit on the plan
- Constraints decrease the speed of the optimisation as they restrict solutions available to the optimisation algorithm
Example of Dose Shaping ROI’s
In IMRT/VMAT dose shaping ROIs are used (e.g. ROI Rings)
What is a conflict in planning and how can it be overcome?
- A conflict is occurs when a volume is under the influence of opposing constraints
- ROI Expansion/Contraction to remove overlaps between ROI’s
-> then allows for dose objectives to be applied to each
individual ROI
Primary Benefits of Inverse Planning - IMRT/VMAT (compared to Forward Planning)
- Better target coverage
- Better quality of life
- Greater OAR sparing
- Improvement in departmental workflow
Summary of ICRU 83
- Emphasis on statistics (homogeneity, conformity, biological metrics)
- No longer use ICRU ref point
- Prescription and reporting with dose volume specifications
ICRU 83 Dose Volume Histogram Metric Specifications
- Dmedian = D50%
- Prescriptive Value = e.g. D95%
- Near Minimum = D98%
- Near Maximum = D2%
What is a fluence map?
- Modulated beam’s radiation fluence as a visual illustration in beam’s eye view in colour or in grayscale
Abbreviations in VMAT Arc Direction
CCW = Counter-Clockwise
CW = Clockwise
Constant Dose Rate (CDR) in VMAT Planning
- Normal VMAT plan requires the LINAC to deliver variable dose rate beam output along with variable gantry speeds
- CDR VMAT plans have a constant MU/degree throughout the sequence
Why should the collimator angle be offset in VMAT Planning?
- Minimise the streaking effects as a result of the interleaf leakage
- Interleaf leakage is still present, but will be scattered
- 5 degree collimator offset is acceptable
What is the difference between Qualitative Evaluation and Quantitative Evaluation?
- Qualitative Evaluation = Slice by Slice Evaluation
- Quantitative Evaluation = Use Metrics (HI Index) (CI Index)
Homogeneity Index (HI)
- An objective tool to analyse the uniformity of dose distribution in the target volume
- Directly calculated from the statistics of the DVH
- HI = (D2%-D98%) / D50%
D2% = Dose received by 2% of the PTV volume
D98% - Dose received by 98% of the PTV volume
D50% = Median absorbed dose received by 50% of the volume
RTOG Conformity Index (CI)
- Relation between the volume of the reference dose (VRI) and the target volume (TV)
- CI = VRI/TV
How to find VRI in the RTOG Conformity Index?
- Convert 95% isodose line into the contour
- Check the volume of the 95% isodose structure relative to the volume of the target structure
Limitation of the conformity index (CI)
- The CI index alone cannot provide any practical information
- With this method alone, compliance with the treatment plan can only be assess by visualisation of CT sections and DVH’s
Biological Metrics
- Treatment plans can also be evaluated by biological metrics
- TCP
- NTCP
ICRU62 information
3DCRT
Ref point positioning
Dmax, Dmean, Dmin, Dref
Dose prescription
What is EUD
Dose if given uniformly to a ROI will produce the same biological response as the heterogenous dose distribution for the ROI
A<1 for target structures, increases cold spots
A=1 for parallel structures, considers hot and cold spots equally
A>1 for serial structures, reduces hot spots