Review Flashcards
How long does morning stiffness last for OA?
< 30 minutes
How long does morning stiffness last for RA?
> 30 minutes
What nodes are seen in OA?
Heberden’s (DIP) and Bouchard (PIP) nodes
What is the age of onset for OA?
Older >65
What is the age of onset for RA?
20-40
What is the speed of onset for OA?
Many yrs
What is the speed of onset for RA?
Rapid, weeks to months
What joints are affected by OA?
Often begins unilateral and limited to one set of joints (ie fingers)
What joints are affected by RA?
Symmetrical polyarticular (small (MCPs) and large joints)
When does joint pain occurs with OA?
Worsens w/ usage of joint
When does joint pain occurs with RA?
At rest, may improve w/ usage of joint
Do systemic sxs occur with OA, if so what are the sxs?
No
Do systemic sxs occur with RA, if so what are the sxs?
Yes, fatigue and malaise
What is seen on an spine XR for RA?
Atlantoaxial subluxation and insatiably (c-spine)
What is seen on an chest XR in a RA pt w/ exposure to silica dust, asbestos fibers, and other pneumoconiosis?
Caplan syndrome: multiple rheumatoid nodules w/ possible cavitation.
What is seen on a hand XR in a pt with Psoriatic arthritis?
- Pencil in a cup deformity d/t erosion of distal end and one phalanx and expansion of the base of the proximal portion of the next phalanx
What is seen on a spine XR in a pt w/ ankylosing spondylosis?
- Sacroiliitis: sclerotic changes of sacroiliac area (SI joint fusion)
- Bamboo spine
What is seen on an XR in a pt w/gout?
Rat-bite erosions
What labs are used to diagnose RA?
- RF
- Anti-CCP (anti-cyclic citrullinated peptides/protome antibody - ACPA)
What is the crystal composition of gout?
Monosodium urate monohydrate (needle like)
What is the crystal composition of pseudogout?
Calcium pyrophosphate (rhomboid like)
What is stage 1 of gout?
Asymptomatic hyperuricemia
What is stage 2 of gout?
Acute gouty arthritis: Podagra (big toe at the first MTP)
What is stage 3 of gout?
Intercritical gout: asymptomatic period after initial attack.
What is stage 4 of gout?
Chronic tophaceous gout - Tophi (conglomerations of urate crystals surrounded by giant cells in an inflammatory rxn
Infections involving GI and GU tracts (campylobacter and chlamydia), staph areus is causes to what disease?
Reactive arthritis
What dx would you think of if a young male comes in complaining of decreased ROM in is back?
Ankylosing spondylosis
Pt comes in with a rash on their leg and joint pain. You do an XR of their hands and you see “pencil in cup”. What do you diagnose pt with?
Psoriatic arthritis
What is the indications for Arthrocentesis?
- Painful joint effusions
- Monoarticular inflammation of joint
- Systemic rheumatoid disorder of unknown etiology
- Articular inflammation of unknown causes
- Bursal aspiration- indicated when there is a painful bursal swelling despite conserving treatment or when olecranon bursitis is aggregated by normal activities
What are the contraindications of Arthrocentesis?
- Total joint replacement
- Burns, infected skin, infected subcutaneous tissue
What is the causes of OA?
- Degenerative condition (wear and tear of cartilage)
- Age
- Obesity
- Excessive joint loading
- Repeated microtrauma
- Macrotruama
- Genetic predisposing
What is the cause of RA?
- Unknown
- may be caused by infxn or series of infxn (most likely viral), and genetically predisposition
What is the cause of Psoriatic Arthritis?
Genetics, +HLA-B27
What is the cause of Reactive arthritis?
Infections involving GI and GU tracts (campylobacter, chlamydia, staph areus)
What lab is + for CREST?
Anti-centromere
What lab is + for drug induced lupus?
Anti-histone antibodies
What labs are + for Sjögrens?
Ro=SS-A and La= SS-B
A positive HLA-B27 would make you think of which 3 disease?
- Ankylosing spondylosis
- Reactive arthritis
- Psoriatic arthritis
What is the COD for drug induced lupus?
Death usually related to cardiac or pulmonary complications.
- 5 yr survival w/o tx
- 10 yr survival w/treatment
What are the general characteristics associated with Polymyalgia rheumatica?
- Temporal arthritis
- Stiffness and subjective weakness of shoulder and hip regions after a period of inactivity
- ESR > 50
- Age >50
What are the SICCA sxs associated with Sjögrens?
SICCA symptoms: dry mouth (xerostomia), dry eyes (xerophthalmia)
Decreases production of saliva and tears
What is the MC non-sicca sx associated with Sjögrens?
Chronic fatigue
What are the general characteristics of Behçet disease?
- Middle eastern descent
- Relapsing uveitis
- Recurring genital ulcers
- Recurring oral ulcers
What are the general characteristics of Takaysau?
- Asian women
- 10-20 yrs old
- Granulomatous vasculitis of aortic arch and its major branches
- Absent peripheral pulses, discrepancies in blood pressure, arterial bruits
What are the general characteristics Granulomatosis with polyangiitis?
- Vasculitis involving the kidneys and upper and lower respiratory tract.
- URI sxs: purulent/bloody nasal discharge, oral ulcerations, hemoptysis, dyspnea, tracheal stenosis
- Saddle nose
What lab is + for Granulomatosis with polyangiitis?
c-ANCA
What is the MCC of death in a pt w/ Granulomatosis with polyangiitis?
Renal failure
What are the general characteristics of SLE?
- Malar butterfly rash
- Photosensitivity
- Discoid lesions
- Oral ulcers
- Alopecia
- Reynaud phenomenon
What are the general characteristics of Dermatomyositis?
- Heliotrope rash: around eyes
- Gottron papules: purplish, papular, erythematous, scaly lesion over the knuckles
- V sign: rash on face, neck and anterior chest
- Shawl sign: rash on shoulder, upper back, elbows and knees
- Increased incidence of malignancy in adults
What does CREST stand for?
C: calcinosis cutis R: reynaud's phenomenon (1st and MC) E: esophageal dysmotility S: sclerodactyly (claw like appearance of hands) T: telangiectasias
What drugs cause drug induced lupus?
- Procainamide
- Hydralazine
- Isoniazide
- Quinidine
- Carbamazepine
- Phenytoin
Is Takayasu large medium or small vasculitis?
Large
Is Behçet disease large medium or small vasculitis?
Medium
Is granulomatosis with polyangiitis large medium or small vasculitis?
Small
What are characteristic findings in a pt with SCFE?
- Risk for AVN
- Obese, adolescent male (13 yrs old)
- Limp
What is the Salter Harris classification?
- S: separated (physis alone)
- A: above (physis and metaphysis)
- L: below (physis and epiphysis)
- TE: through everything (physis, metaphysis, and epiphysis)
- R: cRush (physis)
Where is the pain located with trochanteric bursitis?
Point tenderness over bursa-pain to lateral aspect of the hip that is made worse w/ direct pressure
What are common sxs of trochanteric bursitis?
- Increased pain in the AM, pain at night, and difficulty laying on the affected side.
- Increased Q angle
- “Snapping” hip syndrome
- +/- warmth
What is the largest Sesamoid bone?
Patella w/quadriceps tendons
What are the types of knee XRs?
- AP
- Lateral
- Sunrise/skyline (axial patellofemoral) - imaging device at 15 degrees and knee at 115 degrees
What zone is a jones fx?
Zone 2
- Fx at 5th MT at the metaphysis/diaphysis junction
Pt with a jones fx is at risk for what?
- Risk for nonunion
- Surgical intervention recommended
What is a common presentation in a pt with RC tendonitis?
- Pain w/ raising the arm overhead
- Age: 40s
- Chronic shoulder pain for months
- Pain worse at night, difficulty sleeping on affected side
Where is the location of pain in a pt with RC tendonitis?
- Localized to the lateral shoulder and radiates to the deltoid muscle
- Tears generally originate in the supraspinatus tendon.
What ligaments are involved with an inversion ankle sprain?
- anterior talofibular ligament
- calceneofibular ligament
- posterior talofibular ligament
What ligaments and structure are involved with an eversion ankle sprain?
deltoid ligament
What are PE findings in a pt with De Quervains?
- Tenderness over the first dorsal compartment of the distal radius
- Swelling over radial styloid
- Crepitus when pt flexes and extends the thumb
- Gripping/making a fist causes pain
What test is used to dx De Quervains?
- Finkelstein test: Full flexion of the thumb into the palm followed by ulnar deviation of the wrist
What is the the tx for De Quervains?
RICE, spica splint, NSAIDs
What is Osgood Schlatter disease?
- Overuse injury in a growing child that results from receptive stress when quadriceps pull on the apophysis of the tibial tubercle during a time of rapid growth
Who is Osgood Schlatter disease seen in more commonly?
- 11-15 yr olds: more common in boys than girls
- Pts who are active in sports
Pain from Osgood Schlatter disease is typically exacerbated when doing what?
Running, jumping, climbing stairs, and squatting.
Why should you get a comparison view in pediatric pts?
Helpful in differentiating a true fracture from a growth plate.
What is the MC cause of compartment syndrome?
Tibial fracture (injury to lower extremities)
What is the hallmark sx of compartment syndrome?
Severe leg pain out of proportion to what would be expected
What are PE findings of a pt with compartment syndrome?
Unwilling to flex and extend extremities
How many compartments in in your thigh and lower leg?
3 in thigh and 4 in lower leg
What is the tx for compartment syndrome?
Immediate fasciotomy within 4-6 hrs
What PE test are used to determine the stability of the knee and what ligament is it testing?
- Varus stress test: LCL
- Valgus stress test: MCL
- Anterior drawer test: ACL
- Posterior drawer test: PCL
- McMurrys: meniscus
- Lachmans: ACL and PCL
What PE test are used to determine the stability of the ankle and what ligament is it testing?
- Anterior drawer test: talofibular ligament
- Varus stress test: calcaneofibular ligament
- Thompson: Achilles tendon
- Talar tilt test: anterior talofibular ligament and calcaneofibular ligament
What are indications to look for a talar dome fx?
Chronic swelling and or locking of the ankle 4-5wks post injury
What is the MC cause of a talar dome fx?
Inversion ankle injuries
What structures are involved in a Lisfranc fx?
Midfoot: tarsometatarsal joint
What would you see on an XR in a pt with a Lisfranc fx?
- Displaced laterally
- Widening between big toe and 2nd toe
A critical injury causing a Lisfranc fx involves what?
- 2nd metatarsal joint, it wedges into a slot in the cuneiforms
What structures are associated with a deltoid injury?
Tear to deltoid ligament usually occurs with a fracture to medial malleolus and distal tibia
Where does the deltoid ligament originate from?
Medial malleolus and spreads to attached to the medial border of the talus