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Shelf - Psychiatry > Review > Flashcards

Review Flashcards

1
Q

MOA of haloperidol

A

D2 receptor antagonist

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2
Q

AE of haloperidol

A

HyperPRL and EPS

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3
Q

Name the tract that causes positive sx in schizophrenia.

A

Mesolimbic tract

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4
Q

Name the tract that haloperidol’s D2 receptor antagonist affects that causes heyper PRL - dop inhibits PRL release, so decreased dop = incr PRL

A

Tubuloinfundibular

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5
Q

Name the tract that haloperidol’s D2 receptor antagonist affects that causes EPS

A

Nigrostriatal

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6
Q

Potency and SE of chlorpromazine and thioridazine

A

Less EPS, more anticholinergic (wet)

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7
Q

What antipsychotic has SE: purple grey metallic rash over sun exposed ares.

A

Chlorpromazine

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8
Q

What antipsychotic has SE: prolonged QTc and pigmentary retinopathy
?

A

Thoridazine

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9
Q

Tx of akathesia

A

Decrease antipsychotic dose and propanolol, or benzo

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10
Q

Tx of acute dystonia dt antipsychotic (presents w/i 12hr)

A

Benztropine or diphenhydramine

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11
Q

Tx of TD

A

Stop antipsychotic and switch to clozapine

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12
Q

Tx of NMS

A

Dantrolene or bromocriptine

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13
Q

Atipical antipsychotic w/ highest risk of EPS and hyperPRL.

What is speccial about adminitration - when do you use?

A

Risperidone

Availabe in depo form

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14
Q

Wt neutral antipsychotic but prolongs QTC

A

Ziprazodone (QTzzzzzz)

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15
Q

Wt neutral byt increases akathesia

A

Aripiprazole (Akathesia = Arapiprazole)

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16
Q

Antipsychotic Most assoc w. Wt gain and sedation

A

Olanzapine (O=big belly)

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17
Q

What antipsychotic causes orthostasis and ataracts?

A

Quetiapine

18
Q

MC SE of clozapine.

A

Sedation and weight gain

19
Q

What labs should you get with clozapine?

A

CBC for leukocytosis

Lipids and cholesterol dt increase caused by clozapine

20
Q

Uses for SSRIs (six)

A 
MDD
Bulemia
Anorexia
PTSD
OCD

Premature ejaculation

21
Q

Name the SSRI that you do not have to taper

A

Fluoxetine

22
Q

Describe 5HT discontinuation syndrome

A

HA, n/v/d, dizziness, fatigue

23
Q

N/v/d, tachycardia, HTN, hyperreflexia, MYOCLONIC JERKS

A

5Ht syndrome (SSRI + MAOI)

24
Q

Buproprion is CI in what three types of pts

A

Eating disorder, alcoholics, epileptics

25
Q

What SSRI can cause HTN crisis if taken with St. John’s wart

A

Venlafaxine

26
Q

Pounding head, flushing, nausea, myoclonus after eating cheese, drinking red wine, tkaing decongestant or meperidine

A

HTN crisis dt tyramine ingestion + MAOI

27
Q

Tx MAOI HTN crisis with what

A

Phentolamione (alpha blocker)

28
Q

Failure of dexamethasone suppression test = what abd and what possible disorder

A

High cortisol dt stress, i.e. MDD

29
Q

Stroke where could cause mania in elderly?

A

Right MCA (right frontal hemisphere)

30
Q

What OTC drug can precipitate n/v/d, course tremor, ataxia, confusion, slurred speech in a pt taking lithium

A

NSAIDs - dont take advil

Aspirin ius better

31
Q

T wave flattening or u wave inversion indivative of…

A

Lithium toxicithy.

32
Q

Clearance of lithium v. Depakote

A

Lithium is renally cleared.

Depakote is hepatically cleared.

33
Q

Bipolar + SJS

A

Lamotrigine

34
Q

Bipolar + elevated LFTs and hep

A

Depakote

35
Q

Bipolar = agranulocytosis

A

Carbamazepine

36
Q

Bipolar - two drugs that increase AFP in pregnant woman

Preferred treatment for bipolar in pregnancy

A

Valporate or carbamazepine

clonazEpam is preferred

37
Q

Social anxiety tx

A

SSRI orSNRI

CBT

If PERFORMANCE BASED - then Bblocker or benzo

38
Q

GAD definition - three or more of…

A

Significant impairment and

Restlessness/feeling on edge
Fatigue
Difficulty concentrating
Irritability 
Muscle tension
Sleep disturbance
39
Q

Acute stress disorder v. PTSD

A

LIFE THREATENING EVENT:

Sx less than one mo of sx = Acute Stress Disorder
Sx greater than one mo of sx = PTSD

40
Q

Define adjustmentn disorder and time frame.

A

Non-life threatening event; followed by significant impairment in function.
Behavior/mood changes after w/i 3mo of stressful event.

41
Q

Define persistent grief: onset and lasting how long

A

Onset - >6m

Lasts 12mo or more

Shelf - Psychiatry (1 decks)

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