Review

Question 1

What is the eqn for filtered load?

Answer 1

Pcr X GFR

Question 2

What is the eqn for GFR?

Answer 2

Ucr*U(ml/min)/Pcr

The best endogenous estimator of GFR is creatinine because it is only slightly secreted in the PT so its excretion rate is essentially equal to its GFR. Inulin is an exogenous substance that could also be used

Question 3

What is the eqn for renal plasma flow?

Answer 3

UPAH* urine flow rate (ml/min)/PlasmaPAH

Question 4

What is the eqn for filtration fraction?

Answer 4

GFR/RPF

Question 5

How do the kidneys respond to low solute levels in the body?

Answer 5

By conserving those electrolytes. Thus, if you’re in a state of hypokalemia (for instance) you would expect the urine potassium to be very low because it is being conserved if the body is functioning correctly but if its high then something is dysfunction

Question 6

Which would show more signs of volume depletion, a person who lost 2L of isotonic fluid or a person who lost 2L of water?

Answer 6

The person who lost 2L of isotonic fluid because it would all come from the ECF

Question 7

What would happen to FF if you were hypovolemic?

Answer 7

It would go up

Question 8

What happens to

a) RPF
b) GFR
c) FF

in a hypovolemic state?

Answer 8

a) decrease
b) unchanged
c) increased

Question 9

What happens to

a) RPF
b) GFR
c) FF

in a hypervolemic state?

Answer 9

a) increase
b) unchanged
c) decreased