Review Flashcards
What is the timing and treatment for prehabilitation of the abdominal with Botox? What is the affect of treatment?
2-4 weeks prior
Higher rates of primary closure
What is the treatment of HIV associated lipodystrophy?
ploy-l-lactic acid (Sculptra)
What percentage of infections are accounted for by Biofilms? What is the most common organisms for breast implants?
80%
Staph epidermadis (coag negative staph)
Where is the lumbar artery perforator flap found?
Between erector spinae and the quadratus lumborum
Lumber is found in the quad by the ER
What is the mechanism of action for papavarine? What is the usual concentration? Mechanism?
Phosphodiesterase inhibitors
30mg/dL
Inhibit phosphodiesterase which Inhibit cGMP
What is the management of aromatase inhibitors and tamoxifen for preop, micro cases?
Aromatase inhibitors continue
Tamoxifen stop (data inconclusive, 28 days prior)
What is a viable option for Poland syndrome? What vessel if IMA is not available?
Diep flap reconstruction
Thoacodorsal artery may be an option for anastomosis
What is the cause of osteogenesis imperfecta?
Type I collagen production
What is the first sign of scleroderma? What is the progression in the fingers? What is the leading cause of death?
Systemic sclerosis disease
Raynaud’s phenomena
Progresses from distal to proximal in the finger
What is xeroderma pigmentosa?
Autosomal recessive disorder affecting the DNA repair, nucleotide excision repair
Early skin cancer development, sensitivity to light
Non melanoma skin cancer by 8-9 years old
What is the defect in Marfans syndrome?
Fibrilin 1
What is the enzyme necessary for collagen cross linking and what viatamin is needed?
Lysyl oxidase and requires
vitamin C
What is implicated in Menke’s disease?
Defect in copper transport
Leads to poor muscle tone, failure to thrive, brittle hair
Where is the defect on the abdominal wall in omphalocele and gastroischesis?
Omphalocele: central abdomen
Gastroischisis: right of the umbilicus
Why does omphalocele happen? When does the intestines herniate and return to the abdomen?
Failure of intestines to return to the abdominal cavity
Herniate week 6 return week 10
What are eccrine glands classified as and what are they important in?
Exocrine sweat glands
Implicated in thermoregulation
What is silver nitrate effective against adverse reactions and what is the most common use? Side effect?
Effective against staph and pseudomonas
Toxic epidermal necrolysis
Electrolyte disturbances
What is a side effect of silver sulfadiazine? What to do
Transient leukopenia
Switching to a different topical for a few days will return the count to normal
What are the intraoperatice factors contributing to flap thrombosis?
Anastomosing irradiated vessels
Intraop hypotension and large volume fluid administration
What is the treatment for melanoma of the nail bed? In situ etc
Wide local excision based on depth with local flap
No need for amputation
What is the most effective technique to minimize costal cartilage warping?
Harvesting the central portion of the rib
What is the defect in Mayer Rotinsky Hauser syndrome? What is present?
Congenital disorder of Mullarien duct aplasia
Ovaries and normal external genitalia
Can be abscence of vagina or abscence of both vagina and uterus
What is PAIS and CAIS syndrome? What are they genetically and what do they all have?
Complete or partial androgen insensitivity syndrome
All have undescended testes and testosterone in the male range
What is Klienfelter syndrome? What do they present with?
47 XXY small testes and testicular insufficiency
What is McKusik Kaufman syndrome?
Present with hydrometricolpos (distal vaginal obstruction
Postaxial polydactyl
Congenital cardiac defects
Four types ranging from imperforate hymen to vaginal atresia with cloacal abnormalities
What is the flap of choice for a type IB posterior vaginal wall defects when abdominoplasty and bilateral medial thigh lift was done?
Free ALT flap
What are the effects of tretinoin? What is the main pharmaceutical mechanism of action?
Increased epidermal and dermal thickness
Thinning of the stratum corneum
MOA inhibition of AP1 transcription factor binding to DNA decreasing protease activity
How does vitamin A help in corticosteroid wound healing issues?
Promotes re epithelialization
What are the effects of long term corticosteroid use on the three phases of wound healing?
1: inflammatory: decrease the expression of cytokines
2: proliferatice: decrease keratinocyte growth factor (driver of re epithelialization)
3: remodeling: decreased macrophages no conversion of type 3 collagen to type I leading to less tensile strength
What type of fluid is TPN in terms of tonicity? What can be helpful in extrav injuries?
Hypertonic
Hyluronidase
Where is the plane of dissection for a transversus abdominis release? Above and below the arcuate line
Between transversus abdominis and transversalis fascia above
Between peritoneum and transversus abdominis below
What is the plan for a tap block?
Between transversus abdominis and internal oblique
Where are morel levalle lesions and what is the treatment?
Located between the deep fat and the deep fascia
Lesions with 400ccs or less would be considered for drain and doxycycline
Larger treat with open surgery and quilting
What are the skin layers from superficial to deep?
Dermis, subq fat, superficial fascia, deep fat, deep fascia, muscle, bone
What is the primary indication for closure of a neural tube defect?
Risk of infection, close within 48hrs
What is the effect of venous repair for venous outflow of the ear?
No change in survival rates
Decreases postoperative need for transfusion
What is the treatment for distal third of the leg defects in patients with severe PVD?
ALT free flap, can be flow through
What are the advantages of prepec placement for breast reconstruction vs sub pec?
Medial placement of implant
Less animation deformity
What is the basic design of the keystone flap?
V to y flaps at the opposing poles at 90 degrees
1:1 flap to defect length
Relies on central random perforators
Ok to release deep fascia surrounding the defect
What is the Gibson principle for cartilage grafting?
Cartilage warps to the opposite side of scoring. Based on the principle of releasing internal self locked stress
Ex a concave piece of cartilage is scored at the concave portion will make it straight
What are the three main flaps to fill pelvic dead space?
VRAM
Gracilis
Omental flaps
What is the blood supply of the para scapular flap and what does it branch off of?
Circumflex scapular artery
Branches off of the sub scapular artery of the axillary artery
Transverse scapular (Supra scapular) and dorsal scapular artery(transverse cervicle)
What is a flap used for vaginal reconstruction that can provide a sensation?
Pudendal fasciocutaneous flaps
Based on the terminal branches of the internal pudendal ateries (superficial perineal arteries)
What is the antibiotic duration for breast reconstruction?
Less than 24 hrs, ancef
What is the affect of vein grafting on digital reimplantation?
Does not decrease success
What are positive predictors of digital replant?
High volume centers
Warm ischemia time less than 12hrs
Cold ischemia time 24hrs
In RFFF penile reconstruction what nerves are coapted for erogenous sensation?
LABC to dorsal nerve of the penis
What is type 1 and type 2 nec fasc?
Type I: polymicrobial
Type II: monomicrobial
What is the treatment for strep pyogenes? What aesthetic procedure may be associated?
Gram positive cocci in chains, Group A strep, beta hemolytic
Treat with Clindamycin and PCN
Liposuction
What is another indication for chest wall reconstruction besides rib space and number?
Paralyzed diaphragm and herniation of abdominal contents below the level of the defect
Need to reconstruct with rigid or semirigid approach
What is the flap of choice for trochanteric defects?
TFL flap
What are flap options for ischial injury reconstruction?
Gracilis and biceps femoris
What is the treatment of choice for lower eternal defects?
Omental flap and skin graft or vram flap
What is the suture of choice for closure of oral mucosal lacerations?
Chromic gut suture
Loses tensile strength in 10-14 days
What is the prophylaxis for leech therapy? What is the organism?
Ciprofloxacin
Aeromonas
What is the best laser for hypervascular burn scar management? What wavelength?
PDL 585nm
Targets hemoglobin at 585nm
What is the hernia working group classification of hernias?
Grade 1 low risk no infection
Grade 2 comorbidities present that increase the risk of complications
Grade 3 discontinuity of the GI tract or wound infection
Grade 4 mesh infection
What is the transformation rate to SCC for leukoplakia of the mouth?
10%
What are the nerve transfers for C5-6 brachial plexus injuries? What time frame?
12-18 months
Spinal accessory to suprascapular nerve for shoulder abduction
Triceps branch of the radial nerve to axillary nerve transfer
Ulnar nerve to biceps transfer
Median nerve to to brachialis muscle branch
What are options for nerve transfer if total plexus injury?
Phrenic to musculocutaneous
What distal nerve transfer can be used for high ulnar nerve injuries?
Ain to ulnar motor branch
What percentage of patients undergoing lower extremity amputation walk when related to critical limb ischemia?
Less than 50%
Compared to post traumatic patients which is over 90%
How much of preserved proximal tibia is needed for the best functional outcome of below the amputation?
At least 10 cm
What is the path of dissection for free fibula flap?
Posterior septum
Peroneus Longus and brevis dissected off the fibula
Anterior septum is identified and divided
EDL muscle encountered first then EHL
Interosseous septum divided and Tibialis posterior identified and dissected off posterior trunk
What is the treatment for arterial thrombosis of the hand for example in ulnar hammer syndrome?
Catheter based arteriogrophy first
What is the management of dupuytrens flare?
NSAIDS rest elevation
What is the Budapest criteria for CPRS?
1 Continued pain out of proportion to original event
- Three of the following (history):
A: numbness or increased pain
B: temperature asymmetry skin color changes
C: edema or sweating
D: decreased motor function or changes in hair or nail growth
(Physical) one symptom needs to be seen at time of evaluation in two of the categories
What is a tendon transfer for foot drop?
Tibialis posterior to foot
What is the treatment of choice for slac wrist?
Scaphoidectomy and four corner arthodesis
What is the Paneva Holevich technique for tendon repair?
Two stage technique where distal ends of the FDS and FDP, sutured to each other, lumbrical sutured over and a silicone rod is left in place for tendon sheath reconstruction.
Second stage the myotendenous junction is then released and pulled through the reconstructed sheath
What is the nerve transfer for foot drop?
Tibial nerve from FHL, FDL to tibialis anterior
What length is nerve grafts not successful?
Over 6cm
What is Olliers syndrome?
Both have Multiple endochondromas
Mafucci has multiple venous malformations
Olliers: no venous malformations
Both can transform to chondrosarcoma
Mutations in IDH 1 and 2
What is the receptor that is overactive in raynauds?
Alpha 2
What causes nail plate deformity from mucous cyst and where?
Eminates from the dip joint and presses on the germinal matrix causing the deformation of the nail
What is the treatment for Marjolins ulcer?
Squamous cell from chronic wounds, very aggressive
Need to treat with resection down to fascia, 2cm margins
What prevents the dorsal dislocations from re locating?
Volar plate, can divide and no need to repair
What is the cause of claw toe?
Injury to the FHL causing contraction and shortening after free fibula
What is the most common primary malignant bone tumor of the hand?
Chondrosarcoma