Review Flashcards
Name 8 investigations for iron deficiency anemia.
- Serum Hemoglobin
- Mean Cell Volume
- Serum Ferritin
- Peripheral blood smear
- Serum iron
- Total iron binding capacity
- Colonoscopy
- Beta-hCG
Thalassemia risk regions (#6)
- Africa
- Middle East
- Mediterranean
- Caribbean
- South East Asia
- South America
Risk factors for vitamin B12 deficiency (#6)
- Gastric surgery
- Strict vegans
- Breastfed children of strict vegans
- Elderly
- Psychiatric
- Pernicious anemia
Investigations for Pernicious Anemia (#2)
- Serum vitamin B12
- Serum anti-intrinsic factor antibody
Forms of iron supplementation (#3)
- Ferrous fumarate (highest iron content)
- Ferrous sulfate (best for children)
- IV iron dextran
Severe anemia investigations [#2]
- Colonoscopy
- Urinalysis
Causes of acute cough (#6)
- Pneumonia
- Heart failure
- Neoplasm
- Foreign body
- Pneumothorax
- ACE inhibitors
Causes of subacute cough (#2)
- Post-viral
- Infectious (bacterial, viral, fungal, mycobacterial)
Causes of chronic cough (#8)
- Asthma
- GERD
- Upper airway cough syndrome
- COPD
- Parasite
- Cystic fibrosis
- Eosinophilic bronchitis
- Bronchiectasis
PERC rule-out criteria for PE (#8)
- Age < 50
- Oximetry >94% (RA)
- Pulse < 100
- No prior PE or DVT
- No recent surgery or trauma (< 4 weeks)
- No hemoptysis
- No estrogen use
- No unilateral leg swelling
Well’s Score for PE (#7)
- Clinical signs & symptoms of DVT
- PE is #1 diagnosis OR equally likely
- HR > 100
- Previous, objectively diagnosed PE or DVT
- Hemoptysis
- Immobilization at least 3 days or surgery in the previous 4 weeks
- Malignancy with treatment within 6 months or palliative
YEARS algorithm to rule out PE if pregnant
- Clinical signs of DVT?
- Hemoptysis?
- PE most likely diagnosis?
0 = rule out PE with D-dimer < 1000 ng /mL
1-3 = rule out PE with D-dimer < 500 ng/mL
Shortness of breath investigations (#7)
- ECG
- Echocardiogram
- Serum Troponin
- Arterial pO2 / pCO2 / pH / HCO3
- Chest x-ray
- Pulmonary function test
- CT chest
Life-threatening causes of dyspnea (#3)
- Foreign body
- Anaphylaxis
- Pneumothorax
Conservative approach to pneumothorax (unilateral, moderate-large, primary spontaneous)
- Observe for 4 hours, discharge if stable on x-ray
Pulmonary / Cardiac zebra causes for dyspnea (#9)
- Recurrent or fungal pneumonia
- Fibrosis
- Post-COVID-19 sequelae
- Pleural effusion
- Occasional arrhythmia
- Cardiomyopathy
- Malignancy
- Mycobacterial
- Aortic stenosis
Non-cardiac/pulmonary causes of dyspnea [#8]
- Anxiety
- Altitude
- Abnormal thyroid
- Acid reflux
- Anemia
- Abdomen
- Allergy
- Anti-aerobic (deconditioning)
Stepwise treatment for mild COPD (#2)
- SABA prn
- LAMA or LABA
Stepwise treatment for moderate/severe COPD with low risk for AECOPD (#3)
- LAMA or LABA
- LAMA+LABA
- Triple
Stepwise treatment for moderate/severe COPD with high risk for AECOPD (#3)
- LAMA+LABA or ICS/LABA
- Triple
- Oral
Oral treatments for COPD (#3)
- Roflumilast
- N-acetyl cysteine (NAC)
- Daily Azithromycin
Recommended COPD treatment if blood eosinophils ≥ 300 cells/uL
Use steroid (ICS+LABA > LAMA+LABA)
Avoid ICS for COPD treatment if (#3)
- Serum eosinophils < 100 cells/uL
- History of mycobacterium
- History of repeated pneumonia
Differential for AECOPD [#6]
- Pneumonia
- Pneumothorax
- Pleural effusion
- Pulmonary embolism
- Pulmonary edema due to heart
- Problem on ECG
When to add antibiotics for COPD
- 2-3 Winnipeg symptoms (sputum purulence, sputum volume, dyspnea)
- CRP > 40
Potential bacteria in complicated COPD infections (i.e., empyema, septic, very sick) [#6]
- H. influenza
- S. pneumoniae
- M. catarrhalis
- Klebsiella
- Gram negatives
- Pseudomonas
Non-medical treatments for COPD [#7]
- Smoking cessation
- Exercise
- Acupuncture
- Active mind-body therapy
- Yoga
- Tai chi
- Opioids (palliative)
Differential for pediatric asthma [#5]
- Croup
- Foreign body
- Infection
- Cystic fibrosis
- Tracheomalacia
Features of well controlled asthma [#5]
- Days with symptoms ≤ 2
- Doses of reliever ≤ 2
- Nights with symptoms < 1
- No interference with work/school/exercise
- Infrequent, mild exacerbations
Asthma diagnosis on spirometry
- FEV1/FVC pre-bronchodilator < 0.75
- FEV1 post-bronchodilator ↑ 12% & reversible
PRAM score for severity of airway obstruction [#5]
- O2 saturation
- Suprasternal retractions present
- Scalene muscle contractions present
- Air entry
- Wheeze
Topics to regularly reassess at asthma visits [#7]
- Control
- Risk of exacerbation
- Spirometry or PEF
- Inhaler technique
- Adherence
- Triggers
- Comorbidities
Labs & management of Testicular Cancer
- b-hCG
- AFP
- Lop it off (surgery)
Risk factors for Testicular Cancer
- Cryptorchidism
- Family history
- Personal history
Screening for lung cancer
Low dose CT if age 55-74, 30 pk/yr smoker, current or quit < 15 years ago –> annually up to 3 times
Screening for ovarian cancer
No screening indicated if asymptomatic, low risk
Screening for cervical cancer
Screen 25-69 every 3 years
Screening recommendations for cervical cancer do NOT apply if [#6]
- Never sexually active
- Weakened immune system
- Symptoms of cervical cancer
- Previous abnormal screening results
- Does not have cervix
- Immunosuppressed
Melanoma prevention [#3]
- Sunscreen
- Physical UV blocking
- Avoid tanning beds
High-risk features that should consider referral for 6-monthly fully body examination for melanoma [#7]
- Older, male
- Previous skin cancer
- Family history
- # of Nevi (>15)
- Light skin, red hair
- Multiple sunburns
- Actinic skin damage