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Pharm Remediation > Review > Flashcards

Review Flashcards

1
Q

What organ, if disease is present, effects metabolism of drugs?

A

Liver

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2
Q

If liver disease is present, what is true about the dosage the patient should receive?

A

They require lower dose

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3
Q

Drugs actions and effects within the body

A

Pharmacodynamic

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4
Q

Activities of the drug after it enters the body

Study of drug absorption, distribution, metabolism and excretion

A

Pharmacokinetics

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5
Q

Factors that effect drug response

A 
Age
Weight
Bender
Disease (liver)
Route of administration
Drug use and pregnancy
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6
Q

Most frequent route of drug administration, rarely causes physical discomfort when taken properly

A

Oral

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7
Q

Drug route given directly into the blood via needle or catheter inserted into the vein . Drug action occurs immediately

A

IV

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8
Q

Does transdermal administration have local or systemic effect

A

Systemic

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9
Q

Does topical route have local or systemic effect

A

Local

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10
Q

Does inhalation route cause local or systemic reaction

A

Local

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11
Q

What are the classes of anti depressants

A
  • Tricyclic antidepressant
  • MAOI
  • SSRI
  • SNRI
  • Serotonin reputable inhibitor antagonist
  • Dopamine/norepinephrine trip take inhibitor
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12
Q

What is the general action by which antipsychotics work

A

Block Dopamine

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13
Q

How do anti convulsants work?

A

Reduce the excitability of neurons in the brain

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14
Q

What is the basic action by which local anesthetics work?

A

Prevent initiation of normal nerve impulses

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15
Q

Name 3 classes of action for NSAIDS

A

Analgesics
Antipyridics
Anti inflammatory

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16
Q

Adverse effects of long term NSAID use

A

GI upset,
GI bleed,
Prolonged bleeding

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17
Q

How do Narcotic analgesics work?

A

Bind to opioid receptor, altering perception and response to pain

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18
Q

What is the drug used to reverse the effects of narcotics

A

Naloxone. It is a comptitive antgonist

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19
Q

How do antihistamines work?

A

Block histamine 1 receptors

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20
Q

How do beta blockers work?

A

Block the beta receptors to decrease the heart rate

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21
Q

What do expectorants and mucolytics do?

A

Loosen and mobilize the thick sputum

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22
Q

example of an expectorant

A

Acetylcysteine

23
Q

example of a mucolytic

A

Guaifenesin

24
Q

Name an antiarrhythmia

A

amiodorone

25
Q

Name a diuretic

A

Furosemide

26
Q

Anti Hyperlipidemic-

A
  • Loop Diuretic- furosemide
  • Carbonic anhydrase inhibtors - acetazolamide
  • Osmotic Diuretic- Mannitol
  • Thiazide diuretic -Hydochlorthiazide
  • Potassium sparring- Spironolactone
27
Q

Antacid uses

A

Heart burn
peptic ulcers
gastric reflux
sour stomach

28
Q

Good medication for peptic ulcer

A

Calcium carbomide

29
Q

H2 histamine agonist work how?

A

Reduce the secretion of gastric acid (treat gastric and duodenal ulcer

30
Q

how do antacids work

A

Neutralize the acid

31
Q

how do proton pump inhibitors work?

A

Block the final step in production of acid and mucosa

32
Q

How do antidiarrheals work and name one

A

decrease digestional parystalsis

example: Loperamide

33
Q

Fecal softener

A

Docusate

34
Q

Irritant laxative work how?

A

Increase intestinal parystalsis

35
Q

adverse effect of hemorroid agents

A

tissue atrophy

36
Q

insulin is used for what?

A

type 1 and type 2 diabetes

37
Q

oral antidiabetics are used for what?

A

Type 2 diabetes. these meds increase insulin creation

38
Q

what organs do thyroid hormones influence

A

every organ or tissue

39
Q

patients with what condition get thyroid hormones

A

hypOthyroidism

40
Q

adverse reactions of oral contraceptives

A

venous thromboembolism

41
Q

antivirals do what?

A

inhibit viral replication

42
Q

anti fungals do what?

A

effect cell membranes

43
Q

Name some antifungals

A

Topical:
Clotrimazole
Tolfnaftate

Systemic:
Ketoconazole
Fluconazole
Terbinafine

44
Q

scabacides do what?

A

paralyze and kill scabies

45
Q

permethrin

A

scabicide

46
Q

how often are safe combinations changed

A

6 months or:

whem compromised or at CO disgression

47
Q

Who countersigns narcot RXs given by IDC

A

CO

48
Q

Who is present when destroying medications

A

all CSIB members

49
Q

DD 200

A

investigation of property loss

50
Q

When a controled substance is lost in transit what form is used

A

DEA 106

51
Q

what is an example of an Aminoglycoside

A

Gentomicin

52
Q

what class is Getamicin

A

Aminoglycoside

53
Q

Lincomasides are bacterocidal or bacterstatic?

A

Per TG: Considered Bacteriostatic but bactericidal against some strains of Stapp, Strep and anaerobes such as bacteroides fragilis

Pharm Remediation (1 decks)

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