Review Flashcards
Palivizumab
RSV-mab
Ivermectin
anti-helminth
Griseofulvin
anti-funGal, tinea capitis
Selenium sulfide, 2 diseases
seborrheic dermatitis (dandruff) tinea versicolor
permethrin
lice
spinosad
stronger lice med
dapsone
dermatitis herpetiformis, clustered vesicles from Celiacs
TCA antidote
NaHCO3
Barbiturate antidote
NaHCO3
Benzodiazepine antidote
flumaZenil
Beta blocker antidote
glucagon
Acetaminophen antidote
N-acetylcysteine
Methanol or ethylene glycol antidote
ethanol or fomepizole
organophosphate antidote
Pralidoxime or atropine
Warfarin antidote
Vit K or FFP
tPA antidote
Aminocaproic acid
Heparin antidote
protamine
carbon MO antidote
100% o2
methemoglobin antidote
methylene blue
aspirin antidote
gastric lavage + alkalizing urine
CN antidote
What medication could cause CN poisoning?
Hydroxocobalimin
OD caused from Na-nitroprusside
arsenic antidote
dimercaprol
pramipexole
restless leg syndrome (dopamine agonist)
zolpidem
insomnia
Modafinil
narcolepsy
Sleepwalking tx
clonazepam
methimazole
hyperthyroid
PTU
hyperthyroid, safe in pregnancy
fluvoxamine
SSRI
Duloxetine
SNRI
alprazolam
Xanax
chlorthalidone
thiazide diuretic
misoprostol, 2 uses
cervical ripening
prevents gastric ulcers in chronic NSAID use
tetrabenazine
Huntington’s disease (only use)
bromocriptine
dopamine agonist
tx for hyperprolactinemia
metoclopramide
dopamine antagonist, promotes prolactin release
RBB vs LBB
RBB > V1, V2
LBB > V5, V6
Cardiogenic shock
CO, PCWP, SVR
CO down
PCWP up
SVR up
hypovolemic shock
CO, PCWP, SVR
CO down PCWP down (less blood in system) SVR up
Septic shock
CO, PCWP, SVR
CO up
PCWP down
SVR down
Anaphylactic shock
CO, PCWP, SVR
CO up
PCWP down
SVR down
Neurogenic shock
CO, PCWP, SVR
CO down
PCWP down
SVR down
AAA monitoring
<3 cm → no follow up 3-4cm → q3y 4-5 cm → q1y 5.0-5.5cm → q3m 5.5cm + → surgery
CURB 65
Confusion Uremia (BUN over 20) Respiratory distress (RR over 30) Blood pressure less than 90/60 Age over 65
Score 0-1 → outpt macrolides
Score 2 → inpt macrolide + beta-lactam or just a fluoroquinolone
Score 3+ → ICU with beta lactam and either macrolide or fluoroquinolone
Peutz-Jeghers
mouth nevi colon polyps (hamartomas, SM)
Gardner syndrome vs Turcot syndrome
Gardner: FAP + osteomas (skull)
Turcot: FAP + CNS tumors
Gardeners use their bones
Turncoats use their brain
Lynch vs Cowden
Lynch: colon + endometrial cancer
Cowden: GI + breast + thyroid cancer
Acute interstitial nephritis
Usually secondary to medication (penicillins, everything) or autoimmune,
Leukocyte casts, hematuria, eosinophiluria,
Fever, rash, joint pain
Membranous nephropathy
Most common nephrotic syndrome, due to infections (Hepatitis, syphillis)
Thickening of glomerular BM
Spike and dome
Goodpasture’s
Nephritic syndrome due to ,
Linear anti-glomerular BM antibodies,
Hematuria + hemoptysis,
Focal Segmental Glomerular Sclerosis
Idiopathic nephrotic syndrome
Proteinuria
Hypoalbuminemia → edema
PCKD is assx with…
inacerebral aneurysms
thoracic aorta aneurysm
Gout vs Pseudogout
gout > needle, negative
pseudo> positive, rhomboid
de Quervain’s thyroiditis
same labs as graves (+ ANA), but with no hyperthyroid symptoms
TRH triggers secretion of…
TSH and Prolactin
MEN 1
pituitary
parathyroid
pancreas
MEN2A
Thyroid
Parathyroid
pheo
MEN2B
Thyroid
pheo
mucosal neuroma
Acromegaly will show increased…
IGF-1
B12 vs Folate defiency
B12> elevated MMA + neuro sx
folate > normal MMA
Tx for vWF deficiency
desmopressin
ALL, AML, CLL, CML
ALL → children
AML → Auer rods
CLL → smudge cells, older patients
CML → philadelphia chromosome BCR-ABL, t(9;22), treat with imatinib
decreased haptoglobin indicates
hemolysis
haptoglobin is busy cleaning up lysed RBCs
anti-dsDNA
SLE
anti-Sm
SLE
Anti-histone
Drug induced SLE
anti-SSA
sjogrens
Ro, La
sjogrens
Jo
dermato/polymysositis
anti-mi
2 diseases
primary biliary cirrhosis
dermato/polymyositis
anti-topoisomerase I
systemic sclerosis
anti-centromere
systemic sclerosis, CREST only
Felty syndrome
RA + neutropenia + splenomegaly
c-ANCA vs p-ANCA
c-ANCA: Granulomatosis with polyangiitis
p-ANCA: Eosinophilic granulomatosis with polyangiitis
Sickle cell, joint infection
salmonella
anchovy paste liver abcess
Entameba histolytica
P. jiroveci tx
TMP/SMX
Brown secquard
Ipsilateral motor and positional sensation
Contralateral pain/temp
Wernicke encephalopathy
ACE: Ataxia, Confusion, Eye problems
Thiamine deficiency, alcohol
Burns adult
Head 9% Arms 9% (each) Legs 18% (each) Torso 36% (Genitalia 1%)
Burns children
Head 18% (-1% per year over age 1)
Arms 9% (each)
Legs 14% (each) (+0.5% per year over age 1)
Torso 36%
Pemphigus vulgaris vs bullous pemphigoid
PV → + Nikolsky’s sign, can include oral mucosa, more painful
BP → - Nikolsky’s sign
TORCH
toxo
chorioretinitis,
intracranial calcifications,
hydrocephalus
TORCH
Rubella
sensorineural hearing loss,
cataracts, heart defects,
blueberry muffin
TORCH
CMV
sensorineural hearing loss, periventricular calcifications microcephaly, blueberry muffin, Hepatosplenomegaly
Measels virus type
paramyxo
Rubella virus type
toga
hypopigmented ash leaf spots, shagreen patch (nevus), angiofibromas,
mental retardation
Tuberous sclerosis
café-au-lait spots, neurofibromas, Lisch nodules (hamartomas of the iris)
NF1
café-au-lait, endocrine hyperfunction (elevated GnRH → precocious puberty)
McCune-Albright
café-au-lait, pancytopenia (immunodeficiency), thumb abnormalities, short height,
Fanconi Anemia
Turners syndrome heart defect
bicuspid aortic valve
Kallman syndrome
delayed puberty + anosmia,
low GnRH
Untreated kawasaki’s causes…
how do you treat?
coronary artery aneurysm, treat with aspirin and IVIG
Labs for Babies born from gestational diabetes
Low.... glucose calcium phosphate blood cell counts
Trisomy 13
Patau Cleft lip/Palate holoProsencephaly Polydactyly Heart defects (Pump) Polycystic kidney
Trisomy 18
Edwards syndrome Prominent occiput Rocker Bottom feet Clenched fist with fingers overlapping Low set ears Micrognathia
Trisomy 21
Single palmar crease
Gap between 1st/2nd toe
Duodenal atresia, hirschsprung disease
Atrioventricular septal defects
Pregnancy weight gains
11-20 → Obese (BMI over 30)
15-25 → Overweight (BMI 25-30)
25-35 → NORMAL
35-45 → underweight (BMI <18.5)
Stages of labor
Stage 1 → cervical ripening
- Latent → 0-6cm dilation (14/20hours, multiparous/nulliparous)
- Active → 6+ cm dilation (1.2/1.5 hours)
Stage 2 → Full dilation-delivery (2/3 hours)
Stage 3 → Delivery of placenta (30 min)
Stage 4 → post-delivery
Galeazzi vs monteggia fracture
Galeazzi fracture → diaphyseal radius w/ radioulnar joint disruption
Monteggia fracture → proximal ulna w/ radial head dislocation
OMT Facet joint orientation (the B’s)
BUM BUL BM
cervical thoracic lumbar
Adson vs Wright test
Adson –> scalenes
Wright –> coracoid process + pec minor
Wallenberg’s test
vertebral artery insufficiency (patient holds head in different positions)
Chi square vs unpaired t-test
Chi-square → typical 2x2 table with drug and placebo
Unpaired t-test → differences in 2 independent groups (birth weight of males vs females)
Clinical trials phases
Phase I → healthy people
Phase II → small number of diseased people
Phase III → large randomized, double blind
Phase IV → long term monitoring after release
primary vs secondary prevention
Primary prevention → immunizations
Secondary prevention → Screening of at risk patients
t-score vs z-score
Z-score = SD is known T-score = SD is unknown but estimated
-vaptan
ADH (vasopressin) antagonist, treats SIADH