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Enalapril vs placebo, NYHA IV
CONSENSUS I
Enalapril vs placebo, NYHA II-III
SOLVD
Metoprolol XL vs placebo
MERIT-HF
Carvedilol vs placebo, NYHA III-IV, EF
COPERNICUS
Captopril vs placebo
SAVE
Valsartan vs captopril vs both, post-MI with HF
VALIANT
Valsartan vs placebo on top of ACEi - No difference
Val-HeFT
Spironolactone vs placebo, NYHA III-IV
RALES
Eplerenone vs placebo, post-MI
EPHESUS
Carvedilol vs metoprolol tartrate
COMET
High vs low dose Losartan
HEAAL
Carvedilol vs placebo, post-MI EF
CAPRICORN
Candesartan vs placebo
CHARM
BiV vs RV pacing in heart failure
BLOCK HF
Ultrafiltration vs Lasix
CARRESS HF
Isosorbide dinitrate and hydralazine vs placebo in AA
A-HeFT
Eplerenone vs placebo in NYHA II
EMPHASIS HF
Spironolactone vs placebo in HFpEF
TOPCAT
TAVR vs medical in those unable to do surgery
PARTNER I
TAVR vs SAVR in high risk patients
PARTNER II
Rate vs rhythm control in atrial fibrillation
AFFIRM
Lenient vs strict rate control in AFIb
RACE II