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Intro to Anesthesia Pharmacology > Reversal Drugs > Flashcards

Reversal Drugs Flashcards

0
Q

ATROPINE

Drug class?

A

Tertiary amine anticholinergic

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1
Q 
ATROPINE
Drug class
mg/cc
Dose
Onset
Peak
Duration
A 
Tertiary amine anticholinergic
0.4 mg/cc
0.8-1.2 mg (with neostigmine) adult dose, 15-70 mcg/kg pediatric dose
15-30 sec
2 min
1-2 hours
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2
Q

ATROPINE

mg/cc?

A

0.4 mg/ cc

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3
Q

ATROPINE

Dose?

A

0.8-1.2 mg (with neostigmine) adult dose, 15-70 mcg/kg pediatric dose

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4
Q

ATROPINE

Onset?

A

15-30 sec

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5
Q

ATROPINE

Peak?

A

2 min

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6
Q

ATROPINE

Duration?

A

1-2 hours

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7
Q 
ROBINUL (glycopyrrolate)
Drug class
mg/cc
Dose
Onset
Peak
Duration
A 
Quaternary ammonium anticholinergic 
0.2 mg/cc
10-20 mcg/kg
1 min
5 min
2-4 hours
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8
Q

ROBINUL (glycopyrrolate)

Drug class?

A

Quaternary ammonium anticholinergic

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9
Q

ROBINUL (glycopyrrolate)

mg/cc?

A

0.2 mg/cc

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10
Q

ROBINUL (glycopyrrolate)

Dose?

A

10-20 mcg/kg

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11
Q

ROBINUL (glycopyrrolate)

Onset?

A

1 min

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12
Q

ROBINUL (glycopyrrolate)

Peak?

A

5 min

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13
Q

ROBINUL (glycopyrrolate)

Duration?

A

2-4 hours

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14
Q 
NARCAN (naloxone)
Drug class
mg/cc
Dose
Onset
Peak
Duration
A 
Opioid antagonist 
0.4 mg/cc
1-10 mcg/kg, repeated as required
1-2 min
5-15 min
1-4 hours
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15
Q

NARCAN (naloxone)

Drug class?

A

Opioid antagonist

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16
Q

NARCAN (naloxone)

mg/cc?

A

0.4 mg/cc

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17
Q

NARCAN (naloxone)

Dose?

A

1-10 mcg/kg, repeated as required

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18
Q

NARCAN (naloxone)

Onset?

A

1-2 min

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19
Q

NARCAN (naloxone)

Peak?

A

5-15 min

20
Q

NARCAN (naloxone)

Duration?

A

1-4 hours

21
Q 
ENLON & ENLON PLUS (Edrophonium + Atropine)
Drug class
mg/cc
Dose
Onset
Peak
Duration
A 
Quaternary ammonium anticholinesterase 
10 mg/cc
0.5-1 mg/kg
30-60 sec
1-5 min
5-20 min
22
Q

ENLON & ENLON PLUS (Edrophonium + Atropine)

Drug class?

A

Quaternary ammonium anticholinesterase

23
Q

ENLON & ENLON PLUS (Edrophonium + Atropine)

mg/cc?

A

10 mg/cc

24
Q

ENLON & ENLON PLUS (Edrophonium + Atropine)

Dose?

A

0.5-1 mg/kg

25
Q

ENLON & ENLON PLUS (Edrophonium + Atropine)

Onset?

A

30-60 sec

26
Q

ENLON & ENLON PLUS (Edrophonium + Atropine)

Peak?

A

1-5 min

27
Q

ENLON & ENLON PLUS (Edrophonium + Atropine)

Duration?

A

5-20 min

28
Q 
PROSTIGMINE (neostigmine)
Drug class
mg/cc
Dose
Onset
Peak
Duration
A 
Carbamyl ester anticholinesterase 
0.5 or 1 mg/cc
25-75 mcg/kg
1-3 min
5-7 min
40-60 min
29
Q

PROSTIGMINE (neostigmine)

Drug class?

A

Carbamyl ester anticholinesterase

30
Q

PROSTIGMINE (neostigmine)

mg/cc?

A

0.5 or 1 mg/cc

31
Q

PROSTIGMINE (neostigmine)

Dose?

A

25-75 mcg/kg

32
Q

PROSTIGMINE (neostigmine)

Onset?

A

1-3 min

33
Q

PROSTIGMINE (neostigmine)

Peak?

A

5-7 min

34
Q

PROSTIGMINE (neostigmine)

Duration?

A

40-60 min

35
Q 
REGONAL (pyridostigmine)
Drug class
mg/cc
Dose
Onset
Peak
Duration
A 
Carbamyl ester anticholinesterase 
5 mg/cc
0.1-0.3 mg/kg
2-5 min
5-15 min
90 min
36
Q

REGONAL (pyridostigmine)

Drug class?

A

Carbamyl ester anticholinesterase

37
Q

REGONAL (pyridostigmine)

mg/cc?

A

5 mg/cc

38
Q

REGONAL (pyridostigmine)

Dose?

A

0.1-0.3 mg/kg

39
Q

REGONAL (pyridostigmine)

Onset?

A

2-5 min

40
Q

REGONAL (pyridostigmine)

Peak?

A

5-15 min

41
Q

REGONAL (pyridostigmine)

Duration?

A

90 min

42
Q 
ROMAZICON (flumazenil)
Drug class
mg/cc
Dose
Onset
Peak
Duration
A 
Benzodiazepine antagonist 
1 mg/cc
8-15 mcg/kg, 0.2 mg typical adult dose increments up to 1 mg
1-2 min
6-10 min
30-60 min
43
Q

ROMAZICON (flumazenil)

Drug class?

A

Benzodiazepine antagonist

44
Q

ROMAZICON (flumazenil)

mg/cc?

A

0.1 mg/cc

45
Q

ROMAZICON (flumazenil)

Dose?

A

8-15 mcg/kg, 0.2 mg typical adult dose increments up to 1 mg

46
Q

ROMAZICON (flumazenil)

Onset?

A

1-2 min

47
Q

ROMAZICON (flumazenil)

Peak?

A

6-10 min

48
Q

ROMAZICON (flumazenil)

Duration?

A

30-60 min

Intro to Anesthesia Pharmacology (9 decks)

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