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Intro to Anesthesia Pharmacology > Reversal Drugs > Flashcards

Reversal Drugs Flashcards

0
Q

ATROPINE

Drug class?

A

Tertiary amine anticholinergic

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1
Q 
ATROPINE
Drug class
mg/cc
Dose
Onset
Peak
Duration
A 
Tertiary amine anticholinergic
0.4 mg/cc
0.8-1.2 mg (with neostigmine) adult dose, 15-70 mcg/kg pediatric dose
15-30 sec
2 min
1-2 hours
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2
Q

ATROPINE

mg/cc?

A

0.4 mg/ cc

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3
Q

ATROPINE

Dose?

A

0.8-1.2 mg (with neostigmine) adult dose, 15-70 mcg/kg pediatric dose

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4
Q

ATROPINE

Onset?

A

15-30 sec

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5
Q

ATROPINE

Peak?

A

2 min

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6
Q

ATROPINE

Duration?

A

1-2 hours

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7
Q 
ROBINUL (glycopyrrolate)
Drug class
mg/cc
Dose
Onset
Peak
Duration
A 
Quaternary ammonium anticholinergic 
0.2 mg/cc
10-20 mcg/kg
1 min
5 min
2-4 hours
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8
Q

ROBINUL (glycopyrrolate)

Drug class?

A

Quaternary ammonium anticholinergic

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9
Q

ROBINUL (glycopyrrolate)

mg/cc?

A

0.2 mg/cc

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10
Q

ROBINUL (glycopyrrolate)

Dose?

A

10-20 mcg/kg

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11
Q

ROBINUL (glycopyrrolate)

Onset?

A

1 min

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12
Q

ROBINUL (glycopyrrolate)

Peak?

A

5 min

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13
Q

ROBINUL (glycopyrrolate)

Duration?

A

2-4 hours

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14
Q 
NARCAN (naloxone)
Drug class
mg/cc
Dose
Onset
Peak
Duration
A 
Opioid antagonist 
0.4 mg/cc
1-10 mcg/kg, repeated as required
1-2 min
5-15 min
1-4 hours
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15
Q

NARCAN (naloxone)

Drug class?

A

Opioid antagonist

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16
Q

NARCAN (naloxone)

mg/cc?

A

0.4 mg/cc

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17
Q

NARCAN (naloxone)

Dose?

A

1-10 mcg/kg, repeated as required

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18
Q

NARCAN (naloxone)

Onset?

A

1-2 min

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19
Q

NARCAN (naloxone)

Peak?

20
Q

NARCAN (naloxone)

Duration?

21
Q 
ENLON & ENLON PLUS (Edrophonium + Atropine)
Drug class
mg/cc
Dose
Onset
Peak
Duration
A 
Quaternary ammonium anticholinesterase 
10 mg/cc
0.5-1 mg/kg
30-60 sec
1-5 min
5-20 min
22
Q

ENLON & ENLON PLUS (Edrophonium + Atropine)

Drug class?

A

Quaternary ammonium anticholinesterase

23
Q

ENLON & ENLON PLUS (Edrophonium + Atropine)

mg/cc?

24
ENLON & ENLON PLUS (Edrophonium + Atropine) | Dose?
0.5-1 mg/kg
25
ENLON & ENLON PLUS (Edrophonium + Atropine) | Onset?
30-60 sec
26
ENLON & ENLON PLUS (Edrophonium + Atropine) | Peak?
1-5 min
27
ENLON & ENLON PLUS (Edrophonium + Atropine) | Duration?
5-20 min
28
``` PROSTIGMINE (neostigmine) Drug class mg/cc Dose Onset Peak Duration ```
``` Carbamyl ester anticholinesterase 0.5 or 1 mg/cc 25-75 mcg/kg 1-3 min 5-7 min 40-60 min ```
29
PROSTIGMINE (neostigmine) | Drug class?
Carbamyl ester anticholinesterase
30
PROSTIGMINE (neostigmine) | mg/cc?
0.5 or 1 mg/cc
31
PROSTIGMINE (neostigmine) | Dose?
25-75 mcg/kg
32
PROSTIGMINE (neostigmine) | Onset?
1-3 min
33
PROSTIGMINE (neostigmine) | Peak?
5-7 min
34
PROSTIGMINE (neostigmine) | Duration?
40-60 min
35
``` REGONAL (pyridostigmine) Drug class mg/cc Dose Onset Peak Duration ```
``` Carbamyl ester anticholinesterase 5 mg/cc 0.1-0.3 mg/kg 2-5 min 5-15 min 90 min ```
36
REGONAL (pyridostigmine) | Drug class?
Carbamyl ester anticholinesterase
37
REGONAL (pyridostigmine) | mg/cc?
5 mg/cc
38
REGONAL (pyridostigmine) | Dose?
0.1-0.3 mg/kg
39
REGONAL (pyridostigmine) | Onset?
2-5 min
40
REGONAL (pyridostigmine) | Peak?
5-15 min
41
REGONAL (pyridostigmine) | Duration?
90 min
42
``` ROMAZICON (flumazenil) Drug class mg/cc Dose Onset Peak Duration ```
``` Benzodiazepine antagonist 1 mg/cc 8-15 mcg/kg, 0.2 mg typical adult dose increments up to 1 mg 1-2 min 6-10 min 30-60 min ```
43
ROMAZICON (flumazenil) | Drug class?
Benzodiazepine antagonist
44
ROMAZICON (flumazenil) | mg/cc?
0.1 mg/cc
45
ROMAZICON (flumazenil) | Dose?
8-15 mcg/kg, 0.2 mg typical adult dose increments up to 1 mg
46
ROMAZICON (flumazenil) | Onset?
1-2 min
47
ROMAZICON (flumazenil) | Peak?
6-10 min
48
ROMAZICON (flumazenil) | Duration?
30-60 min

Intro to Anesthesia Pharmacology (9 decks)

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