Retinal Topography And Vasculature Flashcards
What is the retinas job
Innermost part of eye that does transduction and sends signal to brain
What is the retina the window into
The CNS and cardiovascular system
What happens in the retina
- light energy is transformed into a neural signal (phototransduction)
- signal is modified within the retina
- contains the first three cells of the visual pathway: photoreceptors (1st), bipolar cells (2nd), and ganglion cells (3rd)
- interneurons
- neuroglia cells
What must happen for light to reach the 1st order neuron
Light must pass through all layers of the retina to reach the 1st order neuron wher it is converted into neural signal by the process of phototransduction. The signal is modified by the 2nd and 3rd order neurons and sent to the brain
How many layers of the retina
10
What are the inner 9 layers collectively referred to as
The sensory or neural retina
What is the 10th retinal layer
RPE
What are some cell types located within the retina
Many
-photoreceptors, horizontal cells, bipolar cells, amacrine cells, interplexiform cells, ganglion cells, and muller cells
Are all regions of the retina the same
No
What are the outer layers of the retina
Photoreceptor layer
External limiting membrane
Outer nuclear layer
Outer plexiform layer
All dealing with the photoreceptors
What is in the photoreceptor layer
- rod outer segment
- rod inner segment
- cone outer segment
- cone inner segment
What is within the outer nuclear layer
Row of cone nuclei
Multiple rows of rod nuclei
What is within the outer plexiform layer
Contains rod spherules and cone pedicles
What do photoreceptors span
Outer retina (photoreceptor layer, external liming membrane, outer nuclear layer, and outer plexiform layer)
Role of photoreceptors
Absorb light photons and convert them into an electrochemical event (nerve signal) through the process of phototransduction.
Rods and cones
How many cones
5-6mill
What percentage of cones are in the fovea
10%
What do cones detect
Bright illumination (photopic) and color
What are the 3 types of cones
S cones (blue, 420) M cones (green 531) L cones (red 588)
What is the only photoreceptor in the fovea
Cones
What type of cone is NOT in the center of the fovea
S cones
How many rods
92-120 mill
What do rods detect
Dim vision (scotopic)
What do rods contain
Photopgiment, rhodopsin, which is located in the disc membrane
Peak density of rods
In a ring 4.5mm outside the fovea
Are there rods in the fovea
No
Blind spot
ONH
Nasal
20 degrees
Horizontal cells
Lateral processes between the cells
What is the second cell in the chain of phototransudction
Bipolar cells
What do amacrine cells do
Processing
What do muller cells do in the retina
They are the radial glial cells of the retina
Maintain structural support/buffering environment
Where are there astrocytes in the retina
RNFL around blood vessels
What does glaucaom kill
Ganglion cells (3rd one) Stem cells wont work here
Retinitis pigmentosa affects what
Photoreceptors
Stem cells could work here