Reticulo endoplasmatico liso Flashcards

1
Q

Funciones

A

Síntesis de lípidos
Desintoxicación
Regulación de calcio

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2
Q

En donde ocurre la síntesis de lípidos

A

lado citosolico del REL

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3
Q

Sintesis de lipidos

A
  1. Proteinas los llevan del citosol a membrana del REL
  2. Se transfiere un CoA
  3. Añade un glicerol 3 fosfato= acido fosfatitico
  4. Modificaciones enzimáticas
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4
Q

Síntesis de esfingolípidos

A
  1. Ceramida se produce en el REL
  2. Se va al aparato de Golgi
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5
Q

Acidos biliares

A

Digestion y absorcion

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6
Q

Hormonas esteroideas

A

Mineralocorticoides,
glucocorticoides, andrógenos y estrógenos

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7
Q

Por donde pasan los lipidos

A

a través de canales formados por proteínas de transferencia

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8
Q

Formacion de gotas lipidicas

A
  1. Enzimas en membrana del REL sintetizan lipidos
  2. Lipidos se acumulan dentro
  3. Seipina ayuda formacion de gota lipidica
  4. Gota se desprende. Perilipina señaliza a donde va
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9
Q

Fat- Soluble Toxins

A

Fase 1
Oxidacion
Reduccion
Hidrolisis
Hidratacion
Dehalogenation

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10
Q

Water soluble Waste

A

Fase 2
Sulfatacion
Glucoronidation
Glutathione Conjugacion
Acetilacion
Amino and acid conjugation
methylation

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11
Q

Vias de eliminacion Water soluble Waste

A

Urina
Bilis
Stool

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12
Q

Donde estan los canales de Ca

A

Reticulo sarcoplasmico

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