reticular formations Flashcards

1
Q

where can the reticular formations be found

A

in brainstem tegmentum

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2
Q

what are reticular formations

A

mass of neurons and nerve fibers extending from caudal medulla to rostral midbrain

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3
Q

what do reticular formations receives

A

receives input from most sensory systems

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4
Q

what do reticular formations send

A

sends efferent fibers to all CNS levels

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5
Q

what to reticular formations influence

A

skeletal muscle activity, somatic and visceral sensation, ANS and endocrine systems as well as level of consciousness

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6
Q

the reticular formations are deeply placed in ______

A

continuous network of nerve cells and fibers extending from brainstem, subthalamus, hypothalamus and thalamus

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7
Q

what are the 3 longitudinal columns

A

Median column - at median plane: intermediate-sized neurons

Medial column - large neurons

Lateral column - small neurons

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8
Q

what does the raphe nuclei of medulla receive

A

inputs from spinal cord, trigeminal sensory nuclei and periaqueductal gray matter of the midbrain

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9
Q

where does the raphe nuclei of medulla project

A

to cerebellum, dorsal horn of spinal cord and trigeminal nuclei

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10
Q

exp the analgesic effect of electrical stimulation of the midbrain periaqueductal gray

A

from facilitatory input from the periaqueductal gray matter to medullary raphe nuclei and its inhibitory projections on spinothalamic neurons in dorsal horn of spinal cord

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11
Q

what does the raphe nuclei of pons and midbrain receive

A

inputs from prefrontal cortex, limbic system and hypothalamus

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12
Q

where does the raphe nuclei of pons and midbrain project

A

to forebrain, cerebellum and brainstem

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13
Q

involved in pain mechanisms

A

Caudal raphe nuclei

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14
Q

involved with wakefulness, alertness and sleep

A

Rostral raphe nuclei

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15
Q

the paramedian groups receives and projects to ______

A

input from spinal cord, cerebral cortex, vestibular nuclei

project to cerebellum

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16
Q

the medial group receives input from

A

spinal cord, ascending sensory systems, superior colliculus, vestibulocerebellum, hypothalamus and cerebral cortex

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17
Q

the descending projections of the medial group project to ______ and controls ______

A

SC and motor control

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18
Q

the ascending projections of the medial group project to ______ and controls ______

A

intralaminar nuclei of the thalamus and basal cholinergic nuclei (nucleus basalis of Meynert)

consciousness and alertness

19
Q

nucleus reticularis pontis caudalis is responsible for ______

A

paradoxical (REM) sleep

20
Q

lateral group recieves _______

A

Receive input from contralateral red nucleus, spinal cord, trigeminal, auditory and vestibular sensory systems

21
Q

lateral group projects to _______

A

Project to both cerebellar hemispheres and to medial nuclei

22
Q

Pedunculopontine nucleus recieves _____ and is responsible for _________

A

input from cerebral cortex, globus pallidus interna and substantia nigra pars reticulata

Locomotion center

23
Q

parabrachial nucleus recieves _____ and projects _________

A

input from amygdala, nucleus solitarius

Projects to hypothalamus, preoptic
area, amygdala and intralaminar
thalamic nuclei

24
Q

parabrachial nucleus is responsible for _______

A

Autonomic regulation

25
Q

Continuation of reticular formation from brainstem

A

Reticular Nucleus of Thalamus

26
Q

reticular nuc of thalamus receives and projects ______

A

input from cerebral cortex and other thalamic nuclei

Project to other thalamic nuclei

27
Q

NT for reticular nuc of thalamus

A

GABA - inhibitort

28
Q

function of reticular nuc of thalamus

A

Integrating and gating thalamic nuclei activities

29
Q

where does acetylcholine project to

A

Pontomesencephalic region of brainstem - pedunculopontine tegmental nuclei and laterodorsal tegmental nuclei

Basal forebrain

30
Q

deficiency in Acethylcholine

A

Alzheimer’s

31
Q

dopamine is located where

A

Substantia nigra pars compacta

Ventral tegmental area

32
Q

Mesostriatal (nigrostriatal)

A

for movement

33
Q

Mesolimbic

A

Overactivity hallucinations

Schizophrenia - kapag too much dopamine sa mesolimbic

34
Q

Mesocortical

A

function. working memory, attentional aspects

Dysfunction: cognitive deficit and hypokinesia in PD (Parkinson’s disease)

35
Q

Modulation of attention, sleep wake
states and mood

A

Norepinephrine (Noradrenaline)

36
Q

Serotonin is found on

A

Raphe nuclei of brainstem

37
Q

Serotonin is for

A

Sleep, emotion

38
Q

Found in neurons of posterior hypothalamus in tuberomammillary nucleus

A

Histamine

39
Q

Histamine

A

Maintain alert state

40
Q

pacemaker for respiration

A

Pre-BÖtzinger complex

41
Q

located along caudal lateral wall of the fourth ventricle in medulla

A

Area Postrema

42
Q

Contains chemotactic trigger zone

A

Area Postrema

43
Q

Maintain sphincter control

A

Pontine micturition center

44
Q
A