Resuscitation, Anaesthetics,ITU Flashcards
What is the difference between an anaphylaxis and anaphylactoid reaction?
An anaphylactoid reaction is a type of anaphylaxis which does not involve an allergic reaction but is due to direct mast cell degranulation
Anaphylaxis is a severe, life-threatening, generalised or systemic hypersensitivity reaction to a trigger, such as an allergy (NHS UK, 2018; RCPCH, 2011)
What alternative to IV acetylcysteine can you prescribe a patient that has taken a significant paracetamol overdose?
NAC has been given orally at the following dose:
Loading dose:
140 mg/kg given as a 5% solution.
If only a higher percentage is available dilute to 5% with juice/cola or water (Toxbase, 2018).
Maintenance doses:
70 mg/kg as a 5% solution every 4 hours.
(Toxbase, 2018).
Methionine was formerly an option for the treatment of paracetamol poisoning, but has been discontinued in UK (Toxbase, 2018).
What are the common causes of cardiac arrest in pregnancy?
- embolization ( Pulmonary embolism/amniotic fluid )
- antepartum haemorage
- sepsis
- Hypertensive disorder in pregnancy ( pre-eclampsia/eclampsia )
- ACS
- acute aortic dissection
Name TWO modifications of cardiac arrest in pregnancy you should implement as per ALS guidelines?
- Activate Obstetrics Cardiac Arrest and you should get expert help from obstetrician, anaesthetist and neonatologist
- LEFT LATERAL TILT 15-30 degrees
If tilt is not feasible, maintain left uterine displacement manually - Due to potential IVC compression, IV or IO access should be established above diaphragm
- Attempt early intubation due to high risk aspiration secondary to gravid uterus
- Position hands higher on the sternum during CPR for advanced pregnancy
briefly describe the procedure to performing a surgical airway/cricothyrodotomy in a patient that needs an emergency airway
- Perform a laryngeal handshake to identify the cricothyroid membrane
- Perform a transverse stab incision through cricothyroid membrane
- Turn blade through 90 (sharp edge caudally)
- Slide coude tip of bougie along blade into trachea
- Railroad lubricated 6.0mm cuffed tracheal tube into trachea
- Ventilate, inflate cuff and confirm position with capnography
- Secure tube
According to DAS intubation guidelines 2015 - what plans would you set out in order to prepare for a difficult airway ?
Plan A Laryngoscopy
If tracheal intubation is unsuccessful
Plan B Insertion of Supraglottic Airway Device
If you fail to ventilate with a Supraglottic Airway Device
Plan C Final attempt at face mask ventilation
If you cannot intubate and cannot ventilate
Plan D Perform Emergency Front of Neck Access
TRY REMEMBER: laryngoscopy (A ) is a SAD ( 2 )Face mask ventilation ( 3 ) with FONA ( 4 )
What are the standard defib pad position/placement?
right sternal ( below the clavicle ) & left apical ( in mid axillary line at the position of the 6th electrode )
Is external mechanical compression devices more effective than manual chest compression?
Rescucitation council ( UK ) recommends that automated mechanical chest compression devices should not be used routinely to replace manual chest compression
what changes to the standard approcah would you make in resuscitation of a pregnant female in cardiac arrest?
- HIgher hand position for chest compression
- manually displace the uterus to the left
- if it is difficult to place the apical defibrillator electrode, use an anterior-posterior or bi-axillary approach
- consider using tracheal tube 0.5 - 1.0mm smaller than usual
- establish IV access at a level above the diaphragm
- If resuscitation attempts fail to achieve ROSC, consider an immediate caesarian section to deliver the fetus within 5 minutes of the mothers cardiac arrest
Which 2 criteria [0.5 each] should be met to suggest that anaphylaxis is highly likely as per ALS guidelines
- sudden onset and rapid deterioration of symptoms
2. life threatening airway and/ breathing an / circulation problem
What are the life threatening differential diagnosis of anaphylaxis?
- life threatening asthma
- septic shock
- choking
- angioedema
Your patient has been successfully treated for anaphylaxis as per ALS guidelines. Your consultant advises to keep her under observation for 6 hours.
Give ONE reason for keeping her under observation [0.5] and give ONE piece of advice you would give her before sending home after period of observation [0.5]
- possibility of biphasic reaction with incidence of 1-20%
2. possibility of continued absorption of allergen
Can you outline the non-anaesthetic treatments for patients with laryngospasm?
- gentle suction secretions
- high flow oxygen via tight fitting mask
- positive pressure ventilation to splint open the airway
- LArsons maneuvre - which can open the airway and break the spasm. jaw thrust with anterior pressure applied to the mandible in the laryngospasm notch.
Describe Larson’s maneuvre to relieve laryngospasm?
jaw thrust with anterior pressure applied to the mandible in the laryngospasm notch.
can you name the 4 components that make up a mapleson C ( water circuit )?
- reservoir bag
- Fresh Gas flow
- APL valve ( adjustable pressure limiting )
- connection to face mask
What are the 2 main advantages of using a Mapleson C ( water cirsuit ) over a bag valve mask attached to a reservoir bag?
- less resistance to spontaneous breathing - ( because exhaled gas exits via APL )
- reduce barotraum - because mapleson C allows adjustment of pressures in assisted ventialtion
According to ASA classification :
How would you differentiate between Minimal sedation, moderate, deep and GA?
Minimal: ( anxiolysis )
drug induced depression of conciousness in which….
patient responds to normal verbal commands
Moderate Sedation: ( concious sedation)
drug induced depression of conciousness in which…
Patient responds purposefully to verbal commands ( either alone or accompanied by light tactile stimulation )
Deep sedation:
drug induced depression of conciousness in which..
Patient cannot be easily roused, but
responds purposefully to repeated verbal or painful stimuli
GA:
Drug induced loss of conciousness in which…
Patient are not rousable even by painful stimulation
According to ASA classification:
How do you achieve minimal, moderate and deep sedation and what is the minimum monitoring required.
Minimal sedation:
use entonox
monitoring required: pulse oximetry
Moderate sedation:
combination of opiates and benzo’s
monitoring required:
Deep sedation
In a patient whose ETT has become dislodged, outline 4 points in your initial management of this patient?
- call for help ( anaesthetist )
- switch to 100% oxygen
- check the circuit and ett to make sure fully out the
trachea and not blocked or rescuable - use airway maneuvres to open the airway
- use face mask ventilation to re-oxygenate the patient.
What are the most common causes of post-intubation hypoxia?
DOPE:
- Displacement
- Obstruction ( mucous/kinking )
- Pneumothorax
- Equipment failure
- Why is etomidate a good induction agent in trauma patients?
- what is the dose?
- are the side effects?
- explain why it is not a good maintenance agent?
- due to ists cardiovascular stability, causes less hypotension at induction than other agents.
- dose: 0.3mg/kg
- side effects:
- pain on injection
- thrombophlebitis
- nausea and vomiting
- adrenal-cortical suppression
- pain on injection and adrenal cortical depression
Give the IV doses and a unique side effect of the following:
Ketamine dose Thipentone dose propofol dose fentanyl dose etomidate dose
atracurium dose
rocuronium dose
suxemethonium dose
- ketamine 1.5mg/kg ( 1mg/kg acceptable )
- thipentone 3-5mg/kg
- propofol 1-2mg/kg ( 1mg/kg acceptable )
- fentanyl 2-10mcg/kg
- etomidate 0.3mg/kg
- atracurium dose: 0.6mg/kg ( half of rocuronium )
- rocuroniumm: 1.2mg/kg
- depolarising suxemethonium: 1.5mg/kg
- Name the potential side effects of suxemethonium
- What are the complications
- what are the contra-indications
- complications of suxemethonium
- suxemethonium aponea
- malignant hyperthermia
- RHAMBDOMYLISIS (as acomplication of hyperthermia)
- hyperkalaemia
- raised intra-ocular pressure
- major burns ( after 24hours )
- hyperkalaemia
- severe muscle trauma
- spinal cord injury causing paraplegia ( between day 10-100 )
- history of malignant hyperthermia
What is the mechanism of action of ketamine?
What makes it a good agent to use in trauma patients?
NMDA receptor antagonist.
it is cardiovascularly stable and does not cause hypotension and is favoured in trauma patients.
causes tachycardia, increase in blood pressure, CVP & C.O due to an increase in sympathetic tone.
duration of action is 5-10 minutes.
What is the side effects of ketamine?
But what is unique about its properties in comparison to all the other anaesthetic agents?
SIDE EFFECTS OF KETAMINE:
nause, vomiting
Hypertension,
dissociative state
nystagmus, diplopia
UNIQUE QUALITY:
it is the only anaesthetic agent available that has
analgesic, hypnotic, and amnesic properties. can be used IV or IM. also used PO, PR, IN. ( IM dose is 10mg/kg )
What is the ASA classification of patients according to disease/ health status of a patient?
I - fit and healthy
II - mild systemic disease
III - severe systemic disease
VI - severe systemic disease with constant threat to life
V - severe systemic disease with patient moribund not
expected to survive without operation
VI - severe systemic disease with patient declared brain
dead
list 5 Contra-indications to procedural sedation in the ED?
PAtient factors:
- 1- ASA>4
- 2- patient has an allergy to the relevant medication
- 3- high risk for vomiting aspiration
Staff factors:
* 4- appropriately trained staff not available to perform sedation
Equipment factors:
* 5- appropriate monitoring and resuscitation fascilities not available
In a patient on face mask oxygen that needs transfer from ED to THeatres - how would you calculate the oxgygen requirement?
and which oxygen cylinder would you use?
CALCULATION OF OXYGEN REQUIREMENT for a patient on face mask oxygen :
2 x ((FLow ( litres/min ) x duration of transfer time ( minutes ) ))
oxygen cylinder size code:
- C - 170
- D - 340
- E - 680
- F - 1360
COmplication of ventral venous access?
!. pneumothoraz
- haemothorax
- chylothorax
- air embolism
- cardiac arythmia
- arterial puncture
- central venous perforation
What is your IMMEDIATE management for local anaesthetic toxicity according to the AAGBI guidelines?
- Stop injecting the LA
- Call for help
- Maintain the airway and, if necessary, secure it
with a tracheal tube
- Maintain the airway and, if necessary, secure it
- Give 100% oxygen and ensure adequate lung
ventilation (hyperventilation may help by
increasing plasma pH in the presence of metabolic
acidosis)
- Give 100% oxygen and ensure adequate lung
- Confirm or establish intravenous access
- Control seizures: give a benzodiazepine,
thiopental or propofol in small incremental doses
- Control seizures: give a benzodiazepine,
- Consider drawing blood for analysis, but do not
delay definitive treatment to do this
- Consider drawing blood for analysis, but do not
What is the discharge criteria for patients following procedural sedation?
- patient return to their baseline conciousness
- vitals observations return to normal limits for patient
- Respiratory status is not compromised
- N&V, Pain and discomfort has been adressed
What is the criteria for ARDS?
How would you set the ventilator for protective lung ventilation?
- Acute with onset over 1 week or less
- bilateral opascities on cxr/ct consistent with pulmonary oedema
- respiratory failure not fully explained by heart failure
of fluid overlad
Protective lung ventilation:
- calculate ideal body weight (
- select any ventilator mode
- achieve low tidal volume ventilation 6ml/kg
- set RR to maintain optimal minute volume ( not > 35/min)
- aim SP02 88-95%
- increase PEEP with increasing Fi02 aim for plateu pressure <30mmhg
- allow permisive hypercapnoea
4 ventilatory induced lung injury?
- volutrauma
- barotrauma
- atelectrauma
- biotrauma