Results

Question 1

Dupixent Ph2 300qw2 vs PBO

Answer 1

EASI….
-22.9 (rel. drop 68%) / -7.5 (rel. drop 22%)
So absolute risk reduction 3x stronger.

IGA proportion … 30% / 2%

Peak Weekly PRN …
Baseline: 6.34. (1.83) / 6.74(2.07)
Week 16: 3.64(2.39) / 6.05(2.31)
Rel. Drop 46% / Rel. Drop 5%

PRN proportion 3+ reduction
41% / 8%

Body SA : - 30.7 / -7.2
Rel. Drop 58% / Rel. Drop 14%

SCORAD :  
Baseline :   68.5 (12.6) /  67.1 (13.6)
Week 16 :   31.7 (29.6) /  54.7 (22.2)
Abs Drop:   36.8.   / 12.4
Rel. % Drop : 54%   /   18%