Restrictive Lung Dz

Question 1

FEV1/FVC ratio =

Answer 1

Greater than 80%

Question 2

Gonna go through some causes next

Answer 2

ok

Question 3

Goodpasture’s Syndrome thing to remember

Answer 3

Anti-Basement Membrane antibodies

Question 4

Idiopathic Pulmonary Fibrosis

Answer 4

Look for honeycombing

Question 5

Sarcoidosis key feature

Answer 5

Non-caseating granulomas, bilateral hilar lymphadenopathy, High ACE and calcium

Question 6

What are pneumoconioses

Answer 6

Due to inhaled substances… Anthracosis, Silicosis, Asbestosis

Question 7

Anthracosis

Answer 7

associated with coal mines ( Coal Miner’s Lung)

Question 8

Which part of the lungs does it affect?

Answer 8

Upper Lobe

Question 9

Silicosis

Answer 9

Associated with sandblasting

Question 10

What exactly happens In silicosis

Answer 10

The main culprit is MACROPHAGES… they respond to the silica and release fibrogenic factors which lead to fibrosis (which makes sense since they are FIBROGENIC). May increase the susceptibility to TB

Question 11

Silicosis affects what lobes?

Answer 11

upper lobes

Question 12

Asbestosis associated with

Answer 12

shipbuilding, roofing, plumbing

Question 13

Asbestosis affects what lobes

Answer 13

Lower lobes!!!!! Asbestos is the only one of the pneumoconiosis that affects the lower lobes

Question 14

Asbestosis increases your risk of

Answer 14

Bronchogenic carcinoma and mesothelioma

Question 15

Berryliosis associated with

Answer 15

Airplane manufacturing

Question 16

Berryliosis causes

Answer 16

non-caseating granulomas