Restrictive Lung Diseases

Question 1

Restrictive lung disease caused by ILD has what effects on TLC, FRC, and RV?

Answer 1

All are lowered

Question 2

Restrictive lung disease caused by muscle weakness has what effects on TLC, FRC, and RV?

Answer 2

• dec. TLC (can’t inhale fully)
• dec. RV (can’t exhale fully)
• FRC normal (chest wall and lungs are fine)

Question 3

Restrictive lung disease caused by obesity has what effects on TLC, FRC, and RV?

Answer 3

• normal TLC and RV

- dec. FRC (extra weight pushes down on lungs when exhaling)

Question 4

Some ILD produce interstitial patterns (increased density of lines) and other produce alveolar patterns (cotton-wool appearing). Therefore, ILD is better known as

Answer 4

diffuse parenchymal lung disease

Question 5

In contrast to OLD, restricted lung will have ____ FEV1/FVC ratio

Answer 5

high

• increased collagen increases the elastic recoil of the restricted lung

Question 6

When the ILD is expanded by fibrous tissue, the diffusion time for oxygen increases (b/c the barrier is thicker). This impairment in diffusion can be demonstrated through

Answer 6

Hgb desaturation with exertion (b/c exercise makes HR go up –> blood/Hgb moves faster –> Hgb more likely to be desaturated) is the hallmark of ILD

Question 7

Patients with restrictive lung disease from ILD will have a _____ A-a gradient

Answer 7

increased (due to thickening of barrier)

Question 8

Patient with restrictive lung disease from neuromuscular weakness will have a _____ A-a gradient

Answer 8

normal

Question 9

A disease that can mimic ILD is

Answer 9

CHF

Question 10

(ground glass vs. consolidation) _____ suggests active inflammation in ILD

Answer 10

ground glass

Non-specific interstitial pneumonia

Question 11

NSIP is a lung disease that is ______ to immunosuppressive therapy

Answer 11

responsive

Question 12

IPF is a lung disease that is ______ to immunosuppressive therapy

Answer 12

not responsive