Resting And Action Potential Flashcards

1
Q

What type of directionality does signal flow have?

A

Unidirectionality

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2
Q

What two features facilitate rapid communication between cells located far away in the body?

A

high degree of morphological and functional asymmetry

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3
Q

How to neurons excite?

A

Electrically and chemically

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4
Q

What makes neurons excitable?

A

the flow of specific inorganic ions through ion channels

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5
Q

What creates a potential difference across the membrane?

A

A change in charge between the ions

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6
Q

What is the potential difference caused by the flow of ions called?

A

Membrane potential

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7
Q

What is a resting potential?

A
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8
Q

What is the typical resting potential?

A

~ -70mV

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9
Q

What maintains the resting potential of a neuron?

A

sodium potassium pump

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10
Q

What is the sodium to potassium ratio that creates an electrochemical gradient in the sodium potassium pump?

A

3 Na+ ions out for every 2 K+ ions in

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11
Q

What part of the neuron is negatively charged and which part is positively charged?

A

interior of cell (-), exterior (+)

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12
Q

What are voltage gated ion channels categorized under?

A

A class of transmembrane proteins

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13
Q

How are voltage-gated ion channels activated?

A

activated by changes in the electrical membrane potential near the channel

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14
Q

What regulates the opening and closing of channel proteins?

A

The alteration of the conformation of channel proteins due to membrane potential.

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15
Q

What are action potentials?

A

the rapid changes in charge across the membrane that occur when a neuron is firing

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16
Q

What are the three main stages of an action potential?

A

depolarization, repolarization and a refractory period

17
Q

What is depolarization in an action potential?

A

electrical change within a neuron from - to +

18
Q

What is repolarization in an action potential?

A

electrical change within a neuron from + to - when sodium channel close and potassium channels open

19
Q

What is refractory/hyperpolarization in an action potential?

A

Unresponsive to stimulation
Both sodium and potassium pumps are closed. Sodium post assign pump is needed to bring back to resting state.