RESS flashcards for summative
what is a health related state
Outcome or dependant variable
e.g death, disease
What is a determinant
A definite cause
Exposure
Independent variable - potential cause
e.g smoking, age``
Incidence
Probability that a disease occurs/is contracted in population within a period of time
Equation: the number of new cases in the period / the number at risk over the period
Prevalence
the number of cases of disease at a particular time point
Mortality
Proportion of people dying from the disease compared to the rest of the population
Equation: number dying in period from disease / number in population
Case fatality rate
Proportion of people who die from a specified disease among all individuals diagnosed with the disease over a certain period of time
Equation: number dying in period from disease / number with the disease in period
The scientific method
1 - Observe 2- Propose/modify a hypothesis 3 - Test the hypothesis 4 - Reject/do not reject 5 - If reject, modify hypothesis, If don't reject - Test again
Case series
Describes a sample of cases with the same disease, not doing any analysis just describing
Cross-sectional study
Studies a group of people at a single point in time
Cohort study
Examines disease development in groups of people over time
Case-control study
Examines history of groups of people with / without a disease
Ecological study (our projects)
Examines variations between geographical areas
3 types of health outcomes
- Record based
- Biological/clinical
- Clinician/patient-reported
Validity
- Measures accurately what it is meant to measure
- E.g. using BMI rather than weight as a measure of obesity
Reliability
- Give the same result on retesting
- E.g. Weight on a bathroom scale is reliable within around ½ a pound
Responsiveness
- Can detect real changes when they occur
- Death is unresponsive because once you’re dead you’re dead, it cant change.
- E.g. continuous QoL scale rather than categorical
Person-time
- Used as incidence denominator
- a way of determining how many people are at risk
Considering a common, short duration disease such as influenza, which of the following would you expect to see?
- Low incidence, low prevalence
- High incidence, low prevalence
- High incidence, High prevalence
- Low incidence, high prevalence
High incidence, low prevalence. Lots of people get it, but they’re cured quickly so fewer people have it at a single point in time.
Relative risk (or odds ratio)
risk in exposed group / risk in unexposed group
Interpretation of relative risk
- =1 means risk in exposed = risk in unexposed. No benefit or harm
- <1 means risk in exposed < risk in unexposed. Exposure is protective
- > 1 means risk in exposed > risk in unexposed. Exposure is harmful