Responses to cell and tissue injury (necrosis and apoptosis) Flashcards
1
Q
What could cause changed in membrane homeostasis?
A
Hydropic change/oncosis - swelling of water
Fatty change/steatosis - accumulation of fat in the liver e.g.: liver cell is involved in fatty metabolism, NADPH removed for energe/substrates taken up for energy, causes fatty change
2
Q
What can changes in membrane homeostasis result in after a long time?
A
Autophagy - if a cell has too much going on, it starts downsizing by eating itself; becomes smaller and less functional
Atrophy - tissue losing cell size and cell number
3
Q
What does the nature of the injury depend on?
A
Whether it is acute or chronic; mild or sever; what type of cell it is e.g.: neuron or skin cell