Response to infection

Question 1

What is released in sweat that causes bacterial death?

Answer 1

Fatty acids

Question 2

Where are mast cells located?

Answer 2

Connective tissue and mucous membranes

Question 3

What do mast cells do?

Answer 3

Dilate blood vessels, induce inflammation through release of histamines and heparin, recruits macrophages and neutrophils

Question 4

What do NK cells do? Where are they located?

Answer 4

Kill tumour cells and virally infected cells

Circulate in blood

Question 5

Where are dendritic cells located?

Answer 5

Epithelial tissue (eg skin, lung, GI tract)

Question 6

What are monocytes, where are they found?

Answer 6

Differentiate into macrophages and dendritic cells in response to inflammation, stored in spleen

Question 7

What do basophils do?

Answer 7

Defence against parasites, release histamines

Question 8

What do eosionphils do?

Answer 8

Release toxins that kill bacteria and parasites

Cause tissue damage!

Question 9

What does C3a, C3b, C5a, C5b-9 complements do?

Answer 9

C3a: Inflammation
C3b: Opsonization and phagocytosis
C5a: Inflammation
C5b-9: Lysis of microbe

Question 10

What is part of the innate system?

Answer 10

Epithelial barriers, phagocytes, complement system, NK cells

Question 11

How do innate cells recognise pathogens? What do they use?

Answer 11

PAMPs, Pattern recognition receptors