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Pharmacology TEST 2 > Response of peripheral cholinergic receptors > Flashcards

Response of peripheral cholinergic receptors Flashcards

1
Q

Cholingeric receptor and action at SA node

A

M2 Decrease HR

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2
Q

Cholingeric receptor and action at Av node

A

M2 Decrease conduction velocity

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3
Q

Cholingeric receptor and action at atria and ventricles

A

M2 Decrease contractility

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4
Q

Receptor and response to exogenous muscarinic agonists within the VSM (vascular smooth muscle)

A

M3 constriction. Note: no PNS innervation

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5
Q

Receptor and response to exogenous muscarinic agonists within the endothelium

A

NO release and dilation. Note: no PNS innervation

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6
Q

Cholingeric receptor and action at Bronchial muscle

A

M3 Bronchiolar constriction

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7
Q

Cholingeric receptor and action at Bronchial glands

A

M3 Secretion

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8
Q

Cholingeric receptor and action with GI Motility & tone

A

M3 Increase

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9
Q

Cholingeric receptor and action with GI Sphincters

A

M3 Relaxation

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10
Q

Cholingeric receptor and action with GI Proton pumps

A

M3 Secretion

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11
Q

Cholingeric receptor and action with Genitourinary Bladder detrusor

A

M3 Contraction

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12
Q

Cholingeric receptor and action with Genitourinary Trigone & sphincter

A

M3 Relaxation

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13
Q

Cholingeric receptor and action with Iris sphincter muscle

A

M3 Contraction – miosis

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14
Q

Cholingeric receptor and action at Lens ciliary muscle

A

M3 Contract – focus near (cilliary muscle is annular-contraction relaxes zonular fibers-relaxes lens-refracts incident rays more

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15
Q

Cholingeric receptor and action at the Salivary glands

A

M3 Salivation

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16
Q

Cholingeric receptor and action at the Sweat glands

A

M Perspiration

17
Q

Cholingeric receptor and action at the Adrenal medulla

A

N (neuronal subtype) Epinephrine release

18
Q

Cholingeric receptor and action at the Autonomic ganglia (PNS/SNS)

A

N (neuronal subtype) EPSP (excitatory post synaptic potential

19
Q

Cholingeric receptor and action at somatic Skeletal muscle

A

N (neuromuscular subtype) Contraction

Pharmacology TEST 2 (10 decks)

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