Respiratory Tract Infection Flashcards

1
Q

Most common cause of CA bacterial pneumonia?

A

Strep. pneumoniae

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2
Q

Most common cause of CA viral pneumonia?

A

influenza virus

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3
Q

Most common cause of hospital acquired pneumonia?

A

gram negative microbes (Klebsiella pneumoniae, E. coli, Enterobacter, Proteus, etc.)

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4
Q

How is CA pneumonia treated in an inpatient vs. outpatient setting?

A
  • Inpatient: macrolide + beta-lactam

- Outpatient: macrolides or doxycycline + respiratory FQ if co-morbid illness or recent antibiotic therapy

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5
Q

What are the syndromes under the diagnosis of Upper Respiratory Tract Infection (URI)?

A
  • Rhinitis
  • Sinusitis
  • Otitis
  • Pharyngitis
  • Laryngotracheitis
  • Epiglottitis
  • Bronchitis
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6
Q

The vast majority of URIs are [viral/bacterial].

A

viral and self-limited

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7
Q

synonymous with the “common cold”

A

infectious rhinitis

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8
Q

Most common cause of infectious rhinitis (common cold)?

A

Rhinovirus (however, no etiologic agent is identified in more than half of cases because the cause is not investigated, as knowing the cause will not change management)

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9
Q

What is the benefit to treating strep throat?

A

It prevents the severe potential complications (rheumatic fever and post-strep glomerulonephritis), but it does not change the course/duration of the pharyngitis itself.

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10
Q

Why is epiglottitis being seen less commonly?

A

because it is commonly due to H. flu, and infants are being immunized against H. flu

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11
Q

Recommended treatment for bronchitis?

A

Etiologic agents are most commonly viral, so antibiotics are NOT recommended. Treatment consists of supportive care (rest, fluids). Anti-tussives and cough syrups generally do not have much of an effect.

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12
Q

What are the 5 ways that pathogens can enter the lungs and cause pneumonia?

A
  • direct inhalation
  • aspiration of upper airway contents
  • spread along mucous membranes
  • hematogenous spread
  • direct penetration (rare)
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13
Q

What are the clinical predisposing factors for pneumonia?

A
  • old age
  • underlying pulmonary disease
  • smoking
  • recent viral illness
  • diabetes mellitus
  • chronic kidney disease
  • immunodeficiency
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14
Q

How do patients with CA bacterial pneumonia present?

A

fever, shaking chills, rusty colored sputum, dyspnea, and pleuritic chest pain

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15
Q

What is a commonly used score to predict mortality for community acquired pneumonia patients?

A
CURB-65
C=Confusion
U=Uremia (BUN >19)
R=RR >30
B=BP <90/60
65=65+ y/o
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16
Q

How is hospital acquired pneumonia treated?

A

anti-pseudomonal cephalosporin, or anti-pseudomonal carbapenem, or beta lactam + beta-lactamase

17
Q

How is aspiration pneumonia treated?

A

beta-lactam + beta-lactamase

18
Q

What is aspiration pneumonia?

A

aspiration of gastric contents into the lung; resulting pneumonia is in part a chemical reaction from irritating effects of the gastric acid

19
Q

Most common cause of chronic pneumonia?

A

slow-growing organisms (Mycobacteria, Nocardia, Actinomyces), endemic fungi, Coxiella, Tularemia

20
Q

Which bacteria can cause necrotizing pneumonia?

A

Staph. aureus, Strep. pneumoniae, Klebsiella, Pseudomonas

21
Q

Most common cause of epiglottitis?

A

H. influenzae