Respiratory System Flashcards
All structures function in air distribution, except:
ALVEOLI
- gas exchange of oxygen and carbon dioxide
Upper Airway Structures
- oronasopharynx
- pharynx
- larynx
- eustachian tube and sinuses
- upper part of trachea
Lower Airway Structures
- trachea
- bronchi
- bronchioles
- alveoli
Diameter of Infant’s Trachea
- approx 4 mm
- presence of edema = increased mucus = bronchospasm = air passage diminished = air flow resistance = increased work of breathing
Diameter of Adult’s Trachea
20 mm
Nose
- nose breathers until 4 weeks
- little mucus (cleansing agent) = susceptible to infection
- very small nasal passage = excess mucus = airway obstruction
Sinuses
INFANTS: born with maxillary and ethmoid sinuses
6-8 YEARS OLD: develop frontal and sphenoid sinus = young children are less susceptible to sinus infection
- frontal sinus = assoc. with infection
Throat
INFANT: tongue relative to oropharynx = larger than adults
- posterior displacement of tongue = severe airway obstruction
EARLY SCHOOL AGE: enlarged tonsillar and adenoidal tissue even in absence of illness = increased incidence of airway obstruction
Cricoid Cartilage
- hyaline cartilage ring that fully encircles trachea
LESS THAN 10 YEARS OLD: underdeveloped = narrowing of larynx
- mucus and edema = air flow resistance = increased effort
Larynx and Glottis
placed higher in the neck = increased chance of aspiration of foreign material in lower airways
Muscles Supporting the Airway of Children
- less functional than adults
= large amount of soft tissues surrounding trachea and mucus membranes lining the airway = less securely attached compared to adults - increases risk of airway edema and obstruction
- upper airway obstruction = tracheal collapse during inspiration
Bifurcation of Trachea
- contributes to risk of aspiration
CHILDREN: 3rd thoracic vertebra
ADULT: 6th thoracic vertebra
Bronchi and Bronchioles
narrower in infants and children compared to adults = increased risk of airway obstruction (bronchitis/ asthma)
Alveoli
- develop at app. 24 weeks of gestation
TERM INFANT: 50 million alveoli
AFTER BIRTH: growth slows until 3 months of age
7-8 YEARS OLD: 300 million (same with adult)
Chest Wall
- highly compliant (pliable) and fail to support lungs adequately
- respiratory effort diminished = functional residual capacity of lungs greatly reduced
- lack of support, tidal volume of infants and toddlers = independent to diaphragm
- diaphragm movement impaired = intercostal muscles cannot lift chest wall = respiration further compromised
Metabolic Rate and Oxygen Need
- children have higher metabolic rate than adults
- resting respiratory rate = faster
- demand for oxygen = higher
- respiratory distress = develop hypoxemia faster than adults
Fetal Lung Development: Week 4
laryngotracheal groove forms on floor foregut
Fetal Lung Development: Week 5
left and right lung buds push into pericardioperitoneal canal (primordial of pleural cavity)
Fetal Lung Development: Week 6
- descent of heart and lungs into thorax
- pleuroperitoneal foramen closes
Fetal Lung Development: Week 7
lung buds divide into secondary and tertiary bronchi
Fetal Lung Development: Week 24
bronchi divide 14 more times and respiratory bronchioles develop
Fetal Lung Development: Birth
additional 7 division of bronchi
Fetal Lung Histology: Stage 1
PSEUDOGLANDULAR PERIOD (5-17 weeks)
- all major elements of lungs formed except those involved with gas exchange (alveoli)
Fetal Lung Histology: Stage 2
CANALICULAR PERIOD (16-25 weeks)
- bronchi and terminal bronchioles increase in lumen size and lungs become vascularized
Fetal Lung Histology: Stage 3
TERMINAL SAC PERIOD (24 weeks- birth)
- more terminal sacs developed with capillaries lined with type I alveolar cells/ pneumocytes
- type II pneumocytes (defenders) secrete surfactant = decrease surface tension forces and aids with expansion of terminal sacs
Fetal Lung Histology: Stage 4
ALVEOLAR PERIOD (late fetal period- 8 years)
- 95% of mature alveoli develop after birth
NEWBORN: only 1⁄6 to 1⁄8 of the adult number of alveoli and lungs appear denser on x-ray