Respiratory Physiology Part 1 Flashcards

lecture 2

1
Q

function of respiratory

A

exchange of oxygen and carbon dioxide b/w the environment and the cells of the body

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2
Q

conducting zone

A

brings air into and out of the lungs

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3
Q

respiratory zone

A

lined with alveoli

gas exchange occurs

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4
Q

structures of conducting zone

A

nose, nasopharynx, larynx, trachea, bronchi, and bronchioles

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5
Q

effects of conducting zone on air

A

it warms, humidifies and filters air before it reaches gas exchange

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6
Q

Mucus and cilia in the conducting zone

A

remove inhaled particles

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7
Q

movement of cilia

A

upward rhythmic beating

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8
Q

what can paralyze cilia / mucus mechanism

A

inhalation of smoke

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9
Q

Sympathetic effects on conducting zone

A

Beta 2 = dilation of airway

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10
Q

Parasympathetic effects on conducting zone

A

muscarinic receptors = contraction

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11
Q

examples of Beta-2

A

epinephrine and albuterol

asthma treatment

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12
Q

structures that participate in respiratory zone

A

bronchioles
alveolar ducts
alveolar sacs
alveoli

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13
Q

bronchioles

A

cilia and smooth muscle

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14
Q

alveolar ducts

A

lined with alveoli

no cilia and very little smooth muscle

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15
Q

gas exchange occurs in

A

alveoli

each lung has 300 million alveoli

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16
Q

why does gas exchange happen rapidly and efficiently

A

alveolar walls are thin and have large surface area

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17
Q

surfactant

A

reduce surface tension of alveoli

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18
Q

what would happen if we didn’t have surfactant

A

the lungs would collapse

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19
Q

macrophages in respiratory zone

A

another line of defense

b/c there is no cilia , macrophages keep alveoli free from dust & debri

20
Q

CO of lungs

A

receive 100% of CO from pulmonary artery (heart)

21
Q

Gravitational effects on pulmonary blood flow

A

Standing –> blood flow is lowest at apex (top) and highest at base (bottom)

Supine–> gravitational effects disappear

22
Q

lung volumes

A

tidal volume
inspiratory reserve volume (IRV)
Expiratory reserve volume (ERV)
Residual volume

23
Q

tidal volume

A

volume of air that fills the alveoli + the volume of air that fills the airway

500 mL

24
Q

Inspiratory reserve volume

IRV

A

additional volume that can be inspired above tidal volume

3000 mL

25
Expiratory reserve volume (ERV)
the additional volume that can be expired below tidal volume 1200 mL
26
Residual volume
volume of gas remaining in the lungs after maximal forced expiration 1200 mL
27
Lung capacities
Inspiratory capacity (IC) Functional Residual Capacity (FRC) Vital Capacity (VC) Total Lung Capacity (TLC)
28
inspiratory capacity (IC)
Tidal volume + Inspiratory reserve volume (IRV) 3500 mL
29
Functional residual capacity (FRC)
expiratory reserve volume (ERV) + residual volume (RV) 2400 mL remaining volume in the lungs after TV is expired
30
FRC can also be thought of as
equilibrium of the lungs
31
Vital Capacity (VC)
inspiratory capacity (IC) + expiratory reserve volume (ERV) 4700 mL volume expired after maximal inspiration
32
vital capacity can increase with
body size male gender physical conditioning
33
total lung compacity (TLC)
all lung volume vital capacity + residual volume 5900 mL
34
Dead Space
volume of the airways and lungs that does not participate in gas exchange
35
Anatomic Space
volume of conducting airways -when tidal volume is inspired, the entire volume does not reach the alveoli for gas exchange
36
At the end of expiration conducting airways are filled with ___
alveolar air -filled with air that has already been in the alveoli and gas exchange
37
After expiring air & the inspiration of the next tidal volume what happens to alveolar air ?
alveolar air is first to enter the alveoli
38
physiologic dead space
total volume of the lungs that does not participate in gas exchange dead space of conducting airways + functional dead space of alveoli
39
ventilation rate
volume of air moved into and out of the air per unit of time
40
minute ventilation
total rate of air movement into & out of the lung Tidal Volume x (breaths/min)
41
alveolar ventilation corrects for
physiologic dead space
42
alveolar ventilation
describes inverse relationship between alveolar ventilation and alveolar PCO2 (the lower the alveolar ventilation , the less CO2 is pulled out of blood & the higher the PaCO2)
43
Alveolar ventilation equation
(TV- Physiologic dead space) x breaths/min
44
Forced Vital Capacity
total volume of air that can be forcibly expired after max inspiration
45
forced vital capacity in healthy lungs
can get all air out in 3 seconds