Respiratory Physiology Flashcards
Diffusion
From high concentration/partial pressure to low concentration/partial pressure
Main mechanism for delivery of O2 to cells
Diffusion
Convection
Movement with a bulk of fluid down stream
How does O2 move around body?
Through movement of heart and lungs
Ficks law of diffusion. What happens as area increase and as thickness increases
Increase of area=increase diffusion
Increase in thickness=decrease diffusion
What happens if pressure difference is zero in ficks law?
No diffusion occurs
Partial pressure of oxygen atmosphere?
Partial pressure muscle?
Frog tissue diffusion
160MmHg
30mmHg
Distance inside tissue where O2 partial pressure reaches 30mmHg is:
1mm
Diffusion is sufficient I’m small animals such as?
Rotifers
O2 requirement increase with mass. What else increases and what decreases?
Diffusion distance and surface area, respectively
As animals get larger what do they require to facilitate diffusion?
Respiratory organs with short diffusion distance and large surface area
Convection
Bulk transport breathing movements
What influences the gas-transfer system structure?
Properties of the medium
Requirements of the animals
What animal has most efficient respiratory system?
Fish. Not birds.
What is the total atmospheric pressure and its composition
760mmHg
N2 600mmHg
O2 160mmHg
What does high altitude reduce?
Atm. pressure. Not % of O2 in the atm.
What happens as water temperature rises?
Solubility of O2 decreases
What fluctuates in water?
% of dissolved O2. Highest in after noon. From 6-18 hours is when photosynthesis best occurs
Animals under what size can rely on simple diffusion?
Animals under 1mm
Gas exchanger in fish?
In mammals?
Secondary lamella
What covers the lungs?
Pleural sac
What makes up the pleural sac
Outer parietal pleura Pleural cavity filled with intramural fluid Visceral pleura (inner)
What does boyles law state?
As volume increases pressure decreases and vice versa
What happens to lungs, diaphragm and muscles during inhalation?
Diaphragm contracts and moves down.
External intercostal muscles contract and lift rib cage up and out.
Lung volume expands
What happens to lungs, diaphragm during exhalation?
Diaphragm and intercostal muscles resting to resting positrons. Rib cage moves down and lungs recoil passively
How much is TLC in humans?
~5.7 L