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NURS 180: PHARMACOLOGY > RESPIRATORY PHARMACOTHERAPY > Flashcards

RESPIRATORY PHARMACOTHERAPY Flashcards

1
Q

Indication for sedating antihistamines

A 
Allergic rhinitis
Anaphylaxis 
Motion sickness
Insomnia (short-term)
Parkinsons Disease
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2
Q

What drug class does the prototype diphenhydramine (Benadryl) belong to?

A

1st generation sedating antihistamines

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3
Q

What drugs belong in the category sedating antihistamines?

A
  • Diphenhydramine (Benadryl)
  • Dimenhydrinate (Dramamine)
  • Promethazine (Pentazine, Phenergan)
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4
Q

Contraindications for sedating antihistamines

A

Infants and children < 2, narrow-angle glaucoma, BPH, acute asthma attack

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5
Q

Sedating antihistamines MOA

A

Binds to H1 receptors blocking the release of histamines

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6
Q

Adverse effects of sedating antihistamines

A

Drowsiness, dizziness, anticholinergic effects (dry mouth, constipation, urinary retention, blurred vision), confusion

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7
Q

Nursing considerations for sedating antihistamines

A
  • Given orally, intranasally, IM, or IV (do not crush enteric-coasted formulations)
  • Take with meals to avoid GI upset
  • Give IV formulation slowly to reduce risk of shock (onset within 15-30 mins)
  • Avoid taking with alcohol and other CNS depressants
  • Avoid activities that require alertness
  • Monitor for anticholinergic effects
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8
Q

Indicaiton for non-sedating antihistamines

A

Allergic rhinitis, chronic idiopathic uticaria

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9
Q

What is the drug class for the prototype ceterizine (Zyrtec)

A

2nd generation non-sedating antihistamine

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10
Q

What drugs belong to the class non-sedating antihistamines?

A
  • Ceterizine (Zyrtec)
  • Loratadine (Claritin)
  • Fexofenadine (Allegra)
  • Desloratadine (Clarinex)
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NURS 180: PHARMACOLOGY (2 decks)

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