Respiratory Exam 1 - COPD Flashcards

1
Q

Mechanisms underlying airflow limitation

A

Small Airways Disease

Parenchymal Destruction

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2
Q

Small Airways Disease

A

Airway inflammation
Airway fibrosis, luminal plugs
Increased airway resistance

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3
Q

Parenchymal Destruction

A

Loss of alveolar attachments

Decrease in elastic recoil

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4
Q

Diagnosis of COPD

A

Spirometry is REQUIRED

Presence of a post-bronchodilator FEV1/FVC <0.70

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5
Q

Normal FEV1

A

4L

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6
Q

Normal FVC

A

5L

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7
Q

Normal FEV1/FVC

A

0.8

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8
Q

COPD Assessment Test (CAT)

A

8-item measure of health status impairment in COPD

Score >/=10 indicates high risk

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9
Q

mMRC Breathlessness Scale

A

Predicts future mortality risk

Stop when pt says no to a question

Score >/=2 indicates high risk

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10
Q

GOLD 1 (Mild)

A

FEV1 >/= 80% of predicted

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11
Q

GOLD 2 (Moderate)

A

50% < 80% of predicted

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12
Q

GOLD 3 (Severe)

A

30% < 50% of predicted

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13
Q

GOLD 4 (Very Severe)

A

FEV1 < 30% of predicted

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14
Q

COPD assessment - exacerbations

A

> /=2 exacerbations in the last year indicates high risk

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15
Q

Patient Group A recommended pharmacotherapy

A

Short Acting Anticholinergic PRN

OR

Short Acting B2-agonist PRN

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16
Q

Patient Group B recommended pharmacotherapy

A

Long Acting Anticholinergic

OR

Long Acting B2-agonist

17
Q

Patient Group C recommended pharmacotherapy

A

Inhaled corticosteroid + Long acting B2-agonist

OR

Long acting anticholinergic

18
Q

Patient Group D recommended pharmacotherapy

A

Inhaled corticosteroid + Long acting B2-agonist

AND/OR

Long acting anticholinergic

19
Q

HandiHaler (Spiriva)

A

Tiotropium

Long Acting Anticholinergic

20
Q

Respimat Combivent

A

Ipratropium
Anticholinergic Agent

Albuterol
Short Acting B2-Agonist

21
Q

Roflumilast (Daliresp)

A

PDE-4 inhibitor (New agent)

22
Q

Theophylline

A

PDE inhibitor (Non-selective