Respiratory Drugs Chapter 37 Flashcards

1
Q

Why is it important to emphasize not overusing Beta Agonists?

A

there is an increased risk of rebound bronchospasm

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2
Q

What is the interaction between Xanthines and smoking?

A

interaction leads to decreased blood concentrations of aminophylline and theophylline.

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3
Q

What is the interaction between Xanthines and charcoal-broiled foods?

A

decreased serum levels of xanthine drugs

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4
Q

What are the adverse effects of Xanthines that must be reported immediately?

A

epigastric pain, nausea, vomiting, tremors and headache

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5
Q

Xanthines can increase CNS stimulation, what foods must be avoided to exacerbate CNS stimulation?

A

foods that contain caffeine

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6
Q

Why must you encourage forcing fluids in patients taking Anticholinergics?

A

to decrease the viscosity of secretion and increase the expectoration of sputum

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7
Q

When should patients be taught to take montelukast?

A

At night

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8
Q

What is the purpose of Leukotriene Receptor Antagonists?

A

Prevention of leukotriene formation and thus preventing/decreasing inflammation, bronchoconstriction, and mucus production

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9
Q

Corticoid inhalers must be primed when?

A

Before the first time using it and if it hasn’t been used in more than 10 days

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10
Q

Should you wash a corticosteroid inhaler or get it wet?

A

No! use a clean, dry cloth or tissue.

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11
Q

What can excess levels of systemic corticosteroids lead to?

A

Cushing’s syndrome, moon face, acne, increase in fat pads and swelling

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12
Q

What could happen if you abruptly stopped taking a systemic corticosteroid?

A

Possibly Addisonian crisis which is nausea, shortness of breath, joint pain, weakness and fatigue

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13
Q

How much of a weight gain should you report when taking corticosteroids?

A

2 pounds or more in 24 hours of 5 pounds or more in 1 week

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14
Q

What changes should you report immediately when taking a Phosphodiesterase-4 inhibitor?

A

Changes in mood or emotions

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15
Q

What is Omalizumab used for?

A

It is a monoclonal antibody antiasthmatic drug that reats moderate to severe asthma and NOT for aborting acute asthma attacks

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16
Q

Xanthines, such as theophylline, how do they work and what are they for?

A

They work by helping relax the smooth muscle of the bronchioles, by inhibiting phosphodiesterase. Phosphodiesterase breaks down cAMP which is needed to relax smooth muscles

17
Q

What are some examples of corticosteroids?

A

beclomethasone, dexamethasone, flunisolide, triamcinolone

18
Q

How do corticosteroids work and what are they for?

A

they stabilize the membranes of cells that release harmful bronchoconstriction substances

19
Q

What are some examples of LTRAs?

A

Zileuton and Zafirlukast

20
Q

What are some of the adverse effects of LTRAs?

A

headache, dizziness, insomnia, and dyspepsia

21
Q

What type of drug is Omalizumab?

A

monoclonal antibody antiasthmatic drug

22
Q

What is Omalizumab used for?

A

the preventative purpose for preventing the release of mediators that lead to allergic responses.