Respiratory Disorders Flashcards
ventilation-perfusion (V/Q)
V — ventilation — the air that reaches the alveoli.
Q — perfusion — the blood that reaches the alveoli via the capillaries.
Want the ratio to be 1:1
V/Q imbalance
when one is higher than the other = “shunting”
physiological shunt (low V/Q ratio)
perfusion (Q) > ventilation (V)
Ex: pneumonia, atelectasis, tumor, mucus plug
alveolar dead space (high V/Q ratio)
ventilation (V) > perfusion (Q)
Ex: PE, pulmonary infarction, cardiogenic shock, mech vents w/high TV
V/Q imbalance - silent unit
both V and Q are inadequate
ex. tension PTX, severe ARDS, chronic bronchitis, emphysema, cystic fibrosis, asthma attack
assessing oxygenation (ratio?) ** diagnostic criteria for lung injury and ARDS
PaO2 / FiO2 ratio
normal = > 400
acute lung injury = 200-300
ARDS = < 200
ex.
PO2 85 mmHg; FiO2 21% = 85/.21=404 (good)
acute respiratory failure criteria
PaO2 < 60 mmHg
OR
PaCo2 > 45 mmHg w/pH <7.35 AND SaO2 <90%
= hypoxemic
acute respiratory failure (ARF) - s/s
check ABGs
dyspnea
hypoxic - restlessness, irritability or agitation, confusion, tachycardia
hypercarbia - decr LOC, HA, drowsiness, lethargy, possible seizures
hallmark of ARF
- hypoxemia
- “50-50 rule” (PaO2 < 60 mmHg and/or PaCO2 > 50 mmHg, pH < 7.3)
type 1 = hypoxemic, normocapnic resp failure
type 2 = hypoxemic, hypercapnic resp failure
ventilatory failure
ventilatory failure = problem in O2 intake
= perfusion is normal but air movement is inadequate
- CO2 is retained
- causes: physical problem of lungs/chest wall; defect in resp center of brain; poor function of diaphragm; atelectasis; mucus plug
- defined by PaCO2 > 45 mmHg + pH < 7.35
oxygenation failure
air moves in and out, but does not oxygenate the pulmonary blood sufficiently (lung blood flow is decreased)
- shunting
- causes: low atmospheric O2; pneumonia; CHF w/PEdema; PEmbolism; ARDS; abnormal hemoglobin; hypovolemic shock; hypoventilation
combined ventilatory and oxygenation failure
involves hypoventilation
CO2 retention
more profound hypoxemia
Who: chronic bronchitis; emphysema; cystic fibrosis, asthma attack
ARF management
- promote adequate gas exchange (supplemental O2, mech vent)
- correct acidosis (O2, sodium bicarb [if pH < 7.2]
- Medications (bronchodilators, steroids, mucolytics, analgesics, sedation, paralytics)
- Nutrition Support
- Promote Secretion Clearance
- Prevent Complications
- Prevent Desaturation
ARF management - positioning
Pts w/V/Q mismatch
place them on the least affected side
ARF management - positioning
Pts w/unilateral lung disease
Place healthy lung in dependent position
ARF management - positioning
Pts w/diffuse lung disease
R lung b/c it’s bigger w/a better lung supply
Pulmonary embolism - s/s
- clot lodged in the pulmonary artery or one of its branches
- s/s occur suddenly
- Classic: dyspnea, sharp, stabbing chest pain, apprehension, restlessness, feeling of impending doom, cough, hemoptysis
- tachypnea
- crackles
- pleural friction rub
- tachycardia
- S3 or S4 heart sound
- diaphoresis
- fever, low grade
- PETECHIAE OVER CHEST AND AXILLAE
- decreased arterial SaO2