Respiratory Disorders Flashcards
Legionnaires Disease
- Legionella Pneumophila
- Gram Negative
- Has extrapulmonary manifestations
- Transmission is droplets via mist
- Incubation 2-10 days
- Diagnose with PCR, urinary antigen, patchy unilobar infiltrates
Acute Bacterial Pneumonia
- Streptococcus Pneumoniae
- resides in respiratory tract of 70% of people
- Transmission via respiratory droplets or aspiration
- incubation 24-48 hours
Septic Pneumonia Manifestations
- Increase WBC
- Increase procalcitonin
- acidosis
- (+) blood culture
- abnormal kidney/liver function
Pneumonia Interventions
- Antibiotic, antifungal, antiviral
- Bronchodilators
- mucolytics, expectorants
- IV fluids
- O2
- diet high in protein, rest
- chest physiotherapy
Aspiration Pneumonia
- Caught through aspiration
- predisposing factors: neurological disorder, upper GI disorder, mechanical disruption
Pneumocytosis Jiroveci Pneumoniae
-Opportunistic
-airborne transmission
-incubation up to 197 days
-diagnosed with:
diffuse, bilateral, interstitial infiltrates
tinctorial staining
fluorescent antibody
PCR
Viral Pneumonia
- airborne transmission
- responsible for 10% of cases
- incubation 2-5 days
- organisms: RSV, flu, adenovirus, measles, covid
Primary Atypical Pneumonia
- Mycoplasma pneumoniae
- gram negative
- manifestation: URI, acute bronchitis, CAP
- transmission: respiratory droplets
- incubation 2-3 weeks
- diagnosis: hemolysis main, patchy opacities, streaks of interstitial infiltrates, areas of atelectasis
Pneumonia Manifestations
Neuro: headache, mood swings, confusion
Respiratory: dyspnea, cough, crackles, sputum, hemoptysis, hypoxia
Cardiovascular: pleuritic pain, tachycardia
Integumentary: fever, chills, fatigue, malaise
gastro: loss of appetite, nausea, vomiting
Pneumonia Classifications
- Community Acquired: streptococcus pneumoniae, influenza
- Healthcare Associated: ventilator associated, pseudomonas aeruginosa, escherichia coli
- Opportunistic: pneumocystis jiroveci, mycobacterium tuberculosis
Pneumonia Pathophysiology
Affects the parenchyma, caused by aspiration of microorganisms thru nasopharynx, they get trapped in cilia and lead to alveolar edema –> dyspnea, hypoxemia
TB Treatment Lengths
Latent: 1 to 2 antibiotics for 12-16 weeks
Active: 3 to 4 antibiotics for 18-31 weeks
TB Pharmacological Treatments
Isoniazid -used for prophylaxis, 1st line treatment -peripheral neuropathy is the # 1 side effect due to B6 deficiency Rifampin -Combination drug -red/orange body fluids is a symptom Ethambutol -treatment of active TB in combination -Optic neuritis is as symptom Pyrazinamide -hepatoxicity
TB isolation precaustions
Airborne isolation precautions
Can be removed if: clinical improvement, on meds minimum of 2 weeks, 3 consecutive negative AFB smears
TB Sputum Tests
Sputum Smear -read in 24 hours -(+) acid fast bacteria -need 3 specimens, 8-24 hours apart Sputum Culture -gold standard -growth of tubercle bacilli -confirms TB diagnosis
TB Blood Tests
IGRA -for people who had BCG -Can't be followed up QuantiFERON TB gold T-spot TB test
TB Skin Test
TST, PPD Test, Mantoux test
- intradermal
- read within 2-3 days
- negative TB test means TB is unlikely
- must have a 2nd test if positive
TB Manifestations
- chest pain
- weight loss
- chills
- long-term cough
- fever
- fatigue
- night sweats
- no appetite
- cough up blood
TB Pathophysiology
TB inhaled thru airborne droplets, they multiply in the alveoli, macrophages and T-Lymphocytes form granulomas, some TB is released when macrophages die and spread in blood
CPAP vs BiPAP
CPAP
-continuous pressure on inhale
BiPAP
-Pressure during inhale and exhale