respiratory Flashcards

1
Q

parts of conductive system

A

nasal cavity, pharynx, larynx, trachea, bronchi

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2
Q

parts of transitional system

A

terminal bronchioles

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3
Q

parts of gas exchange system

A

respiratory bronchioles and alveoli

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4
Q

non-specific immune response

A
  • mucous trapping
  • mucociliary clearance
  • phagocytosis
  • air turbulence- generated by coughing and sneezing
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5
Q

specific immune response

A
  • antibody production
  • antibody-mediated phagocytosis
  • cell- mediated immunity
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6
Q
  1. respiratory region of nasal cavity (largest part)
A
  • respiratory portion lined by psuedostratified columnar epithelium with goblet cells
  • lamina-propria contains tubulo-alveolar glands- mainly serous with lesser numbers of mucous and mixed glands
  • conchae turbinates
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7
Q
  1. vestibular region of nasal cavity
A
  • initial, external part of nasal cavity
  • lined by haired skin and glands
  • stratified squamous keratinized epithelium
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8
Q
  1. olfactory region of nasal cavity
A
  • lined with olfactory epithelium, lacks goblet cells
  • has neurons, supporting cells. basal cells
  • along with respiratory region contain venous plexus with swell bodies
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9
Q

mucociliary apparatus

A
  • pseudostratified ciliated columnar epithelium
  • goblet cells– produce mucinogen granules
  • movement of cilia removes mucus with trapped airborne inhaled particles such as dust and microorganisms
  • cleaning apparatus of upper respiratory passages
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10
Q

larynx

A
  • includes cartilage, vocal folds, skeletal muscle
  • initial part of larynx=stratified squamous epithelium
  • after vocal cords changes to pseudostratified ciliated columnar epithelium
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11
Q

trachea

A
  • lined by ciliated psuedostratified columnar epithelium
  • lamina propria and submucosa are clearly not demarcated
  • serous glands in lamina propria/submucosa
  • cartilagenous rings
  • connective tissue adventitia
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12
Q

bronchus

A
  • ciliated pseudostratified columnar epithelium
  • smooth muscle, lamina propria, mixed bronchiole glands
  • plates of hyaline cartilage
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13
Q

bronchioles

A
  • lack cartilage and glands
  • terminal
  • respiratory
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14
Q

terminal bronchioles

A
  • lined by ciliated cuboidal cells- few to no goblet cells

- muscularis mucosae

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15
Q

club “Clara” cells

A
  • in terminal and respiratory bronchioles
  • bulge at surface
  • secrete surfactant-like substance which aids in maintaining patency of airway
  • may have immune function
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16
Q

respiratory bronchioles

A
  • ciliated cuboidal epithelium
  • incomplete muscularis mucosae
  • subdivide into alveolar ducts
17
Q

alveolar ducts

A
  • exchange system
  • empty into alveolar sacs and alveoli
  • walls are lined with simple squamous epithelial cells
  • opening surrounded by smooth muscle
  • empty into alveolar sacs and alveoli
18
Q

alveolar sacs

A
  • branch from alveolar sacs, lack smooth muscle

- lined by epithelial cells: Pneumocytes type I and pneumocytes type II

19
Q

alveolar pores of Kohn

A
  • neighboring alveoli connect via pores, equalization of pressure and collateral ventilation
  • pores allow macrophage passage from one alveolus to another
20
Q

alveolar septum and interstitium

A
  • fibroblasts and capillaries
  • collagen type 3
  • collagen type 1 always present in conducting airways
  • elastic fibers
21
Q

pneumocyte type 1- squamous alveolar type 1 cell

A
  • form walls of alveoli
  • 95% alveolar surface area
  • thin with occluding junctions to prevent fluid passage
  • not mitotic
22
Q

pneumocyte type II- granular alveolar type II cell

A
  • 5% alveolar surface area
  • secretory cell
  • lamellar bodies produce surfactant
  • can be mitotic and produces type 1 and 2 cells
23
Q

surfactant

A
  • phospholipoprotien
  • reduces surface tension
  • produced by type II cells
  • cortisol stimulates production of surfactant in fetus
24
Q

Air-Blood barrier

A
  • cytoplasm of pneumocyte type I covered by surfactant
  • two fused basal laminae of alveolar epithelium and endothelium of capillary
  • endothelium
25
Q

interalveolar septum

A
  1. granular pneumocyte= great alveolar cell pneumocyte type II
    - granules of surfactant
    - surfactant on surface of alveolar lining
    - cytoplasm of pneumocyte type I
    - pneumocyte type 1
26
Q

pulmonary macrophages

A
  • alveolar macrophages (PAMS)

- intervascular macrophages (PIMS)

27
Q

pleura

A
  • thoracic wall, diaphragm and mediastinum lined by parietal pleura, continuous with mediastinal and visceral pleura covering surfaces of lungs
  • pleura is composed of simple squamous epithelial cells- mesothelial cells