Respiratory Flashcards
What is the general function of alveoli
Gas exchange
Alveolar type:
~95% of alveolar surface
Squamous cell with zonula occludens
Gas exchange
Type I
Alveolar type: Most to sides btwn. alveoli Cuboidal cells NO gas exchange Stem cell for both types I & II Produce pulmonary surfactant and lysozome
Type II
What are dust cells that develop from monocytes to clean septal walls via phagocytosis and produce lysozome
Alveolar Macrophage
What is the interalveolar septum
Region btwn. 2 alveoli
What is the regoin where oxygen and CO2 pass btwn. air and blood
Blood-Gas barrier
What is shared btwn. alveolar type I cells and endothelial cell of capillary
Fused basal lamina
What is the minimum distance/barrier that allows the most efficient gas exchange
Blood-gas barrier
Patches of what kind of epithelium may develop in the upper respiratory tract from too much coughing occurs
Stratified squamous epithelium instead of respiratory epi.
What causes respiratory distress of the newborn
Too few mature alveolar type II cells
What are the 2 tx. for RDS of the newborn
Artificial surfactant and CPAP or Glucocorticoids given before birth to induce surfactant production
What results from a dec. in elastin, reduced surface for gas exchange, and is irreversible
Emphysema
What protein produced by hepatocytes protects elastic fibers
Alpha-1 Antitrypsin