RESPIRATORY Flashcards
When will a D-Dimer always be positive?
In a pregnant woman
How do we know from the doorway if a patient is really sick or not?
Respiratory distress = tripod, use of accessory muscle, drooling, and speaking in 3-4 word sentences, audible wheeze
What’s important about vital signs in the ED setting?
You must always be able to explain abnormal vital signs
What type of questions should you ask in someone with respiratory distress with a history of asthma?
First – use Yes/No questions
Always ask: Have you been intubated before?
Have you been on prednisone?
Is this your asthma?
Are you getting tired?
What are some risk factors to an asthma exacerbation?
Current or recent steroid use
Comorbid conditions
Serious psychiatric illness
Illicit drug use = cocaine
Low socioeconomic class
What else do we need to ask our patient who is having an asthma exacerbation?
Recent illnesses, exposure to triggers, recent increase in use of rescue meds, how long has this been going on for?
What would be a concerning vital sign in asthmatic?
SAO2
What test should you do right away with an asthmatic and best to monitor it throughout (or at the very least after) treatment?
Peak Flow Meter (PFM) & Sit the patient up ☺
What would you see in a child who is in respiratory distress from an asthma exacerbation?
Intercostal retractions & Abdominal breathing
What are some risk factors for death from asthma?
Prior intubation
Previous ICU admission for asthma
Frequent ED visits for asthma
Hospitalization in the past month
Use of 2 or more albuterol inhalers
Use of A/C
What’s our first go to for an asthma exacerbation?
Inhaled Beta2 Agonist (albuterol) – to relax bronchial smooth muscle, decrease histamine release, and increase mucociliary clearance
CONTINUOUS nebulization (adult = 15mg & child = 7.5mg)
Can you use too much albuterol?
Nope
What are some S/E of albuterol?
Tremor & Tachycardia
- Totally normal!!
What do you need to evaluate after each treatment of albuterol?
subjective response, PE, lung function via PFM
What can a patient use if they are allergic to albuterol?
Levalbuterol (Beta 2 receptor agonist with some beta 1 activity)
So if the patient has already tried lots of albuterol at home – hence why they’re now in the ED – what treatment do you turn to?
Steroids!
Which route works fast… PO or IV? What are the names of the meds for PO vs. IV?
They’re EQUAL
But both take 6 hours to work…
PO = Prednisone
IV = Solumedrol
What about inhaled corticosteroids, do those work for an acute exacerbation?
Negative
How do steroids work for asthma exacerbations?
Inhibit airway inflammation, block leukotriene synthesis, and inhibit cytokine production
Well, your patient is already on steroids and used their albuterol inhaler at home – none of those worked so now what?
Epinephrine
How is Epi administered? Who do we use it on? Who do we go easy on the Epi with?
IM route is superior to SC
Use it on the sickest of the sick
But avoid it in old folks with cardiac problems
Okay, so, your patient tried their albuterol and that failed. You gave the person steroids but they take 6 hours to work. You don’t want to use Epi because it’s too intense (or maybe the person is too old)… but the person is still in distress… what do you use?
Terbutaline!
How does Terbutaline work?
Selective beta2 agonist acting directly on beta2 receptors, relaxing bronchial smooth muscle
What’s another asthma medication that is older, rarely used now days, and is for people who have TERRIBLE asthma since it has such a narrow therapeutic window?
Theophyline
You gave Terbutaline (after everything else) and they’re still not doing well… what can you give them?
Magnesium Sulfate!
What asthma medication is especially good for preggo ladies?
Magnesium Sulfate!
What nebulized treatment is the equivalent of about 25% as dense as room air?
Heliox
What are some significant warning signs of severe asthma exacerbation?
PFM 45mmHg
Mental status changes; cardiac arrhythmias, pulsus paradoxus (>20mmHg), and pneumothorax
So, if a patient with an asthma exacerbation looks really, really sick you decide to get blood gases to monitor them – what do you need to pay attention to the most?
PCO2 → if it’s driving upwards, the higher the number, the closer they are getting to respiratory collapse
If a patient in a prolonged asthma attack that is not being cured by usual treatment, what would you notice on PE, that would make you feel it’s time to intubate them?
Silent lungs!! = because they’re not moving air around
You elect to intubate the person – does that solve your problem?
NO
Although you have a secure airway so you can ventilate, that doesn’t mean you can PERFUSE them… so continue with the treatments previously discussed
What would be some criteria for the need to admit an asthma exacerbation?
Repeat visit within 3 days without improvement; changes in mental status; failure of post-treatment PFM to increase by at least 15% or if absolute PFM is
In order to discharge a patient home what must you do?
Prove it to the chart note – document time and changes in sxs after meds and changes/improvements in PFM
What the hell do you do if your tanking asthmatic is pregnant???
Sit her up & do nothing different!!
Although some of the meds are not ideal for baby, if mom doesn’t get better, baby doesn’t survive
So, what are the big take home points from our discussion on asthma exacerbations?
Lots of nebs
Steroids, terbutaline, Epi, Mg Sulfate
Silent chest not your friend
Document re-examinations